3.3AISep 29, 2025
HeDA: An Intelligent Agent System for Heatwave Risk Discovery through Automated Knowledge Graph Construction and Multi-layer Risk Propagation AnalysisYiquan Wang, Tin-Yeh Huang, Qingyun Gao et al.
Heatwaves pose complex cascading risks across interconnected climate, social, and economic systems, but knowledge fragmentation in scientific literature hinders comprehensive understanding of these risk pathways. We introduce HeDA (Heatwave Discovery Agent), an intelligent multi-agent system designed for automated scientific discovery through knowledge graph construction and multi-layer risk propagation analysis. HeDA processes over 10,247 academic papers to construct a comprehensive knowledge graph with 23,156 nodes and 89,472 relationships, employing novel multi-layer risk propagation analysis to systematically identify overlooked risk transmission pathways. Our system achieves 78.9% accuracy on complex question-answering tasks, outperforming state-of-the-art baselines including GPT-4 by 13.7%. Critically, HeDA successfully discovered five previously unidentified high-impact risk chains, such as the pathway where a heatwave leads to a water demand surge, resulting in industrial water restrictions and ultimately causing small business disruption, which were validated through historical case studies and domain expert review. This work presents a new paradigm for AI-driven scientific discovery, providing actionable insights for developing more resilient climate adaptation strategies.
3.6CRApr 24, 2025
Crypto-ncRNA: Non-coding RNA (ncRNA) Based Encryption AlgorithmXu Wang, Yiquan Wang, Tin-yeh Huang
In the looming post-quantum era, traditional cryptographic systems are increasingly vulnerable to quantum computing attacks that can compromise their mathematical foundations. To address this critical challenge, we propose crypto-ncRNA-a bio-convergent cryptographic framework that leverages the dynamic folding properties of non-coding RNA (ncRNA) to generate high-entropy, quantum-resistant keys and produce unpredictable ciphertexts. The framework employs a novel, multi-stage process: encoding plaintext into RNA sequences, predicting and manipulating RNA secondary structures using advanced algorithms, and deriving cryptographic keys through the intrinsic physical unclonability of RNA molecules. Experimental evaluations indicate that, although crypto-ncRNA's encryption speed is marginally lower than that of AES, it significantly outperforms RSA in terms of efficiency and scalability while achieving a 100% pass rate on the NIST SP 800-22 randomness tests. These results demonstrate that crypto-ncRNA offers a promising and robust approach for securing digital infrastructures against the evolving threats posed by quantum computing.