7.3AIJul 29, 2024
Multimodal Large Language Models for Bioimage AnalysisShanghang Zhang, Gaole Dai, Tiejun Huang et al.
Rapid advancements in imaging techniques and analytical methods over the past decade have revolutionized our ability to comprehensively probe the biological world at multiple scales, pinpointing the type, quantity, location, and even temporal dynamics of biomolecules. The surge in data complexity and volume presents significant challenges in translating this wealth of information into knowledge. The recently emerged Multimodal Large Language Models (MLLMs) exhibit strong emergent capacities, such as understanding, analyzing, reasoning, and generalization. With these capabilities, MLLMs hold promise to extract intricate information from biological images and data obtained through various modalities, thereby expediting our biological understanding and aiding in the development of novel computational frameworks. Previously, such capabilities were mostly attributed to humans for interpreting and summarizing meaningful conclusions from comprehensive observations and analysis of biological images. However, the current development of MLLMs shows increasing promise in serving as intelligent assistants or agents for augmenting human researchers in biology research
Training-free Regional Prompting for Diffusion TransformersAnthony Chen, Jianjin Xu, Wenzhao Zheng et al.
Diffusion models have demonstrated excellent capabilities in text-to-image generation. Their semantic understanding (i.e., prompt following) ability has also been greatly improved with large language models (e.g., T5, Llama). However, existing models cannot perfectly handle long and complex text prompts, especially when the text prompts contain various objects with numerous attributes and interrelated spatial relationships. While many regional prompting methods have been proposed for UNet-based models (SD1.5, SDXL), but there are still no implementations based on the recent Diffusion Transformer (DiT) architecture, such as SD3 and FLUX.1.In this report, we propose and implement regional prompting for FLUX.1 based on attention manipulation, which enables DiT with fined-grained compositional text-to-image generation capability in a training-free manner. Code is available at https://github.com/antonioo-c/Regional-Prompting-FLUX.
31.4ROMar 26, 2025
MoLe-VLA: Dynamic Layer-skipping Vision Language Action Model via Mixture-of-Layers for Efficient Robot ManipulationRongyu Zhang, Menghang Dong, Yuan Zhang et al.
Multimodal Large Language Models (MLLMs) excel in understanding complex language and visual data, enabling generalist robotic systems to interpret instructions and perform embodied tasks. Nevertheless, their real-world deployment is hindered by substantial computational and storage demands. Recent insights into the homogeneous patterns in the LLM layer have inspired sparsification techniques to address these challenges, such as early exit and token pruning. However, these methods often neglect the critical role of the final layers that encode the semantic information most relevant to downstream robotic tasks. Aligning with the recent breakthrough of the Shallow Brain Hypothesis (SBH) in neuroscience and the mixture of experts in model sparsification, we conceptualize each LLM layer as an expert and propose a Mixture-of-Layers Vision-Language-Action model (MoLe-VLA, or simply MoLe) architecture for dynamic LLM layer activation. We introduce a Spatial-Temporal Aware Router (STAR) for MoLe to selectively activate only parts of the layers based on the robot's current state, mimicking the brain's distinct signal pathways specialized for cognition and causal reasoning. Additionally, to compensate for the cognitive ability of LLMs lost in MoLe, we devise a Cognition Self-Knowledge Distillation (CogKD) framework. CogKD enhances the understanding of task demands and improves the generation of task-relevant action sequences by leveraging cognitive features. Extensive experiments conducted in both RLBench simulation and real-world environments demonstrate the superiority of MoLe-VLA in both efficiency and performance. Specifically, MoLe-VLA achieves an 8% improvement in the mean success rate across ten tasks while reducing computational costs by up to x5.6 compared to standard LLMs.
7.6CVApr 10, 2024
SpikeNVS: Enhancing Novel View Synthesis from Blurry Images via Spike CameraGaole Dai, Zhenyu Wang, Qinwen Xu et al.
One of the most critical factors in achieving sharp Novel View Synthesis (NVS) using neural field methods like Neural Radiance Fields (NeRF) and 3D Gaussian Splatting (3DGS) is the quality of the training images. However, Conventional RGB cameras are susceptible to motion blur. In contrast, neuromorphic cameras like event and spike cameras inherently capture more comprehensive temporal information, which can provide a sharp representation of the scene as additional training data. Recent methods have explored the integration of event cameras to improve the quality of NVS. The event-RGB approaches have some limitations, such as high training costs and the inability to work effectively in the background. Instead, our study introduces a new method that uses the spike camera to overcome these limitations. By considering texture reconstruction from spike streams as ground truth, we design the Texture from Spike (TfS) loss. Since the spike camera relies on temporal integration instead of temporal differentiation used by event cameras, our proposed TfS loss maintains manageable training costs. It handles foreground objects with backgrounds simultaneously. We also provide a real-world dataset captured with our spike-RGB camera system to facilitate future research endeavors. We conduct extensive experiments using synthetic and real-world datasets to demonstrate that our design can enhance novel view synthesis across NeRF and 3DGS. The code and dataset will be made available for public access.
13.4LGNov 27, 2024
Proactive Gradient Conflict Mitigation in Multi-Task Learning: A Sparse Training PerspectiveZhi Zhang, Jiayi Shen, Congfeng Cao et al.
Advancing towards generalist agents necessitates the concurrent processing of multiple tasks using a unified model, thereby underscoring the growing significance of simultaneous model training on multiple downstream tasks. A common issue in multi-task learning is the occurrence of gradient conflict, which leads to potential competition among different tasks during joint training. This competition often results in improvements in one task at the expense of deterioration in another. Although several optimization methods have been developed to address this issue by manipulating task gradients for better task balancing, they cannot decrease the incidence of gradient conflict. In this paper, we systematically investigate the occurrence of gradient conflict across different methods and propose a strategy to reduce such conflicts through sparse training (ST), wherein only a portion of the model's parameters are updated during training while keeping the rest unchanged. Our extensive experiments demonstrate that ST effectively mitigates conflicting gradients and leads to superior performance. Furthermore, ST can be easily integrated with gradient manipulation techniques, thus enhancing their effectiveness.
17.2ROOct 20, 2025
Robobench: A Comprehensive Evaluation Benchmark for Multimodal Large Language Models as Embodied BrainYulin Luo, Chun-Kai Fan, Menghang Dong et al.
Building robots that can perceive, reason, and act in dynamic, unstructured environments remains a core challenge. Recent embodied systems often adopt a dual-system paradigm, where System 2 handles high-level reasoning while System 1 executes low-level control. In this work, we refer to System 2 as the embodied brain, emphasizing its role as the cognitive core for reasoning and decision-making in manipulation tasks. Given this role, systematic evaluation of the embodied brain is essential. Yet existing benchmarks emphasize execution success, or when targeting high-level reasoning, suffer from incomplete dimensions and limited task realism, offering only a partial picture of cognitive capability. To bridge this gap, we introduce RoboBench, a benchmark that systematically evaluates multimodal large language models (MLLMs) as embodied brains. Motivated by the critical roles across the full manipulation pipeline, RoboBench defines five dimensions-instruction comprehension, perception reasoning, generalized planning, affordance prediction, and failure analysis-spanning 14 capabilities, 25 tasks, and 6092 QA pairs. To ensure realism, we curate datasets across diverse embodiments, attribute-rich objects, and multi-view scenes, drawing from large-scale real robotic data. For planning, RoboBench introduces an evaluation framework, MLLM-as-world-simulator. It evaluate embodied feasibility by simulating whether predicted plans can achieve critical object-state changes. Experiments on 14 MLLMs reveal fundamental limitations: difficulties with implicit instruction comprehension, spatiotemporal reasoning, cross-scenario planning, fine-grained affordance understanding, and execution failure diagnosis. RoboBench provides a comprehensive scaffold to quantify high-level cognition, and guide the development of next-generation embodied MLLMs. The project page is in https://robo-bench.github.io.
2.3AIDec 5, 2024
Expand Heterogeneous Learning Systems with Selective Multi-Source Knowledge FusionGaole Dai, Huatao Xu, Yifan Yang et al.
Expanding existing learning systems to provide high-quality customized models for more domains, such as new users, is challenged by the limited labeled data and the data and device heterogeneities. While knowledge distillation methods could overcome label scarcity and device heterogeneity, they assume the teachers are fully reliable and overlook the data heterogeneity, which prevents the direct adoption of existing models. To address this problem, this paper proposes a framework, HaT, to expand learning systems. It first selects multiple high-quality models from the system at a low cost and then fuses their knowledge by assigning sample-wise weights to their predictions. Later, the fused knowledge is selectively injected into the customized models based on the knowledge quality. Extensive experiments on different tasks, modalities, and settings show that HaT outperforms state-of-the-art baselines by up to 16.5% accuracy and saves up to 39% communication traffic.
2.0LGMay 26, 2023
HUB: Guiding Learned Optimizers with Continuous Prompt TuningGaole Dai, Wei Wu, Ziyu Wang et al.
Learned optimizers are a crucial component of meta-learning. Recent advancements in scalable learned optimizers have demonstrated their superior performance over hand-designed optimizers in various tasks. However, certain characteristics of these models, such as an unstable learning curve, limited ability to handle unseen tasks and network architectures, difficult-to-control behaviours, and poor performance in fine-tuning tasks impede their widespread adoption. To tackle the issue of generalization in scalable learned optimizers, we propose a hybrid-update-based (HUB) optimization strategy inspired by recent advancements in hard prompt tuning and result selection techniques used in large language and vision models. This approach can be easily applied to any task that involves hand-designed or learned optimizer. By incorporating hand-designed optimizers as the second component in our hybrid approach, we are able to retain the benefits of learned optimizers while stabilizing the training process and, more importantly, improving testing performance. We validate our design through a total of 17 tasks, consisting of thirteen training from scratch and four fine-tuning settings. These tasks vary in model sizes, architectures, or dataset sizes, and the competing optimizers are hyperparameter-tuned. We outperform all competitors in 94% of the tasks with better testing performance. Furthermore, we conduct a theoretical analysis to examine the potential impact of our hybrid strategy on the behaviours and inherited traits of learned optimizers.