Lin Tian

CL
h-index36
26papers
667citations
Novelty47%
AI Score60

26 Papers

CVSep 13, 2023Code
$\texttt{NePhi}$: Neural Deformation Fields for Approximately Diffeomorphic Medical Image Registration

Lin Tian, Hastings Greer, Raúl San José Estépar et al. · harvard

This work proposes NePhi, a generalizable neural deformation model which results in approximately diffeomorphic transformations. In contrast to the predominant voxel-based transformation fields used in learning-based registration approaches, NePhi represents deformations functionally, leading to great flexibility within the design space of memory consumption during training and inference, inference time, registration accuracy, as well as transformation regularity. Specifically, NePhi 1) requires less memory compared to voxel-based learning approaches, 2) improves inference speed by predicting latent codes, compared to current existing neural deformation based registration approaches that \emph{only} rely on optimization, 3) improves accuracy via instance optimization, and 4) shows excellent deformation regularity which is highly desirable for medical image registration. We demonstrate the performance of NePhi on a 2D synthetic dataset as well as for real 3D medical image datasets (e.g., lungs and brains). Our results show that NePhi can match the accuracy of voxel-based representations in a single-resolution registration setting. For multi-resolution registration, our method matches the accuracy of current SOTA learning-based registration approaches with instance optimization while reducing memory requirements by a factor of five. Our code is available at https://github.com/uncbiag/NePhi.

IVAug 1, 2024Code
multiGradICON: A Foundation Model for Multimodal Medical Image Registration

Basar Demir, Lin Tian, Thomas Hastings Greer et al. · harvard

Modern medical image registration approaches predict deformations using deep networks. These approaches achieve state-of-the-art (SOTA) registration accuracy and are generally fast. However, deep learning (DL) approaches are, in contrast to conventional non-deep-learning-based approaches, anatomy-specific. Recently, a universal deep registration approach, uniGradICON, has been proposed. However, uniGradICON focuses on monomodal image registration. In this work, we therefore develop multiGradICON as a first step towards universal *multimodal* medical image registration. Specifically, we show that 1) we can train a DL registration model that is suitable for monomodal *and* multimodal registration; 2) loss function randomization can increase multimodal registration accuracy; and 3) training a model with multimodal data helps multimodal generalization. Our code and the multiGradICON model are available at https://github.com/uncbiag/uniGradICON.

CVNov 25, 2023Code
SAME++: A Self-supervised Anatomical eMbeddings Enhanced medical image registration framework using stable sampling and regularized transformation

Lin Tian, Zi Li, Fengze Liu et al. · harvard

Image registration is a fundamental medical image analysis task. Ideally, registration should focus on aligning semantically corresponding voxels, i.e., the same anatomical locations. However, existing methods often optimize similarity measures computed directly on intensities or on hand-crafted features, which lack anatomical semantic information. These similarity measures may lead to sub-optimal solutions where large deformations, complex anatomical differences, or cross-modality imagery exist. In this work, we introduce a fast and accurate method for unsupervised 3D medical image registration building on top of a Self-supervised Anatomical eMbedding (SAM) algorithm, which is capable of computing dense anatomical correspondences between two images at the voxel level. We name our approach SAM-Enhanced registration (SAME++), which decomposes image registration into four steps: affine transformation, coarse deformation, deep non-parametric transformation, and instance optimization. Using SAM embeddings, we enhance these steps by finding more coherent correspondence and providing features with better semantic guidance. We extensively evaluated SAME++ using more than 50 labeled organs on three challenging inter-subject registration tasks of different body parts. As a complete registration framework, SAME++ markedly outperforms leading methods by $4.2\%$ - $8.2\%$ in terms of Dice score while being orders of magnitude faster than numerical optimization-based methods. Code is available at \url{https://github.com/alibaba-damo-academy/same}.

CVJun 13, 2022
$\texttt{GradICON}$: Approximate Diffeomorphisms via Gradient Inverse Consistency

Lin Tian, Hastings Greer, François-Xavier Vialard et al. · harvard

We present an approach to learning regular spatial transformations between image pairs in the context of medical image registration. Contrary to optimization-based registration techniques and many modern learning-based methods, we do not directly penalize transformation irregularities but instead promote transformation regularity via an inverse consistency penalty. We use a neural network to predict a map between a source and a target image as well as the map when swapping the source and target images. Different from existing approaches, we compose these two resulting maps and regularize deviations of the $\bf{Jacobian}$ of this composition from the identity matrix. This regularizer -- $\texttt{GradICON}$ -- results in much better convergence when training registration models compared to promoting inverse consistency of the composition of maps directly while retaining the desirable implicit regularization effects of the latter. We achieve state-of-the-art registration performance on a variety of real-world medical image datasets using a single set of hyperparameters and a single non-dataset-specific training protocol.

CLMar 13, 2023Code
MetaTroll: Few-shot Detection of State-Sponsored Trolls with Transformer Adapters

Lin Tian, Xiuzhen Zhang, Jey Han Lau

State-sponsored trolls are the main actors of influence campaigns on social media and automatic troll detection is important to combat misinformation at scale. Existing troll detection models are developed based on training data for known campaigns (e.g.\ the influence campaign by Russia's Internet Research Agency on the 2016 US Election), and they fall short when dealing with {\em novel} campaigns with new targets. We propose MetaTroll, a text-based troll detection model based on the meta-learning framework that enables high portability and parameter-efficient adaptation to new campaigns using only a handful of labelled samples for few-shot transfer. We introduce \textit{campaign-specific} transformer adapters to MetaTroll to ``memorise'' campaign-specific knowledge so as to tackle catastrophic forgetting, where a model ``forgets'' how to detect trolls from older campaigns due to continual adaptation. Our experiments demonstrate that MetaTroll substantially outperforms baselines and state-of-the-art few-shot text classification models. Lastly, we explore simple approaches to extend MetaTroll to multilingual and multimodal detection. Source code for MetaTroll is available at: https://github.com/ltian678/metatroll-code.git.

CVJul 19, 2023
SAMConvex: Fast Discrete Optimization for CT Registration using Self-supervised Anatomical Embedding and Correlation Pyramid

Zi Li, Lin Tian, Tony C. W. Mok et al. · harvard

Estimating displacement vector field via a cost volume computed in the feature space has shown great success in image registration, but it suffers excessive computation burdens. Moreover, existing feature descriptors only extract local features incapable of representing the global semantic information, which is especially important for solving large transformations. To address the discussed issues, we propose SAMConvex, a fast coarse-to-fine discrete optimization method for CT registration that includes a decoupled convex optimization procedure to obtain deformation fields based on a self-supervised anatomical embedding (SAM) feature extractor that captures both local and global information. To be specific, SAMConvex extracts per-voxel features and builds 6D correlation volumes based on SAM features, and iteratively updates a flow field by performing lookups on the correlation volumes with a coarse-to-fine scheme. SAMConvex outperforms the state-of-the-art learning-based methods and optimization-based methods over two inter-patient registration datasets (Abdomen CT and HeadNeck CT) and one intra-patient registration dataset (Lung CT). Moreover, as an optimization-based method, SAMConvex only takes $\sim2$s ($\sim5s$ with instance optimization) for one paired images.

CVApr 28, 2023
Inverse Consistency by Construction for Multistep Deep Registration

Hastings Greer, Lin Tian, Francois-Xavier Vialard et al. · harvard

Inverse consistency is a desirable property for image registration. We propose a simple technique to make a neural registration network inverse consistent by construction, as a consequence of its structure, as long as it parameterizes its output transform by a Lie group. We extend this technique to multi-step neural registration by composing many such networks in a way that preserves inverse consistency. This multi-step approach also allows for inverse-consistent coarse to fine registration. We evaluate our technique on synthetic 2-D data and four 3-D medical image registration tasks and obtain excellent registration accuracy while assuring inverse consistency.

IVMar 10, 2022
LiftReg: Limited Angle 2D/3D Deformable Registration

Lin Tian, Yueh Z. Lee, Raúl San José Estépar et al. · harvard

We propose LiftReg, a 2D/3D deformable registration approach. LiftReg is a deep registration framework which is trained using sets of digitally reconstructed radiographs (DRR) and computed tomography (CT) image pairs. By using simulated training data, LiftReg can use a high-quality CT-CT image similarity measure, which helps the network to learn a high-quality deformation space. To further improve registration quality and to address the inherent depth ambiguities of very limited angle acquisitions, we propose to use features extracted from the backprojected 2D images and a statistical deformation model. We test our approach on the DirLab lung registration dataset and show that it outperforms an existing learning-based pairwise registration approach.

CLJun 2
Long Live Fine-Tuning: Task-Specific Transformers Outperform Zero-Shot LLMs for Misinformation Response Classification on Reddit

JooYoung Lee, Lin Tian, Angela Brillantes et al.

As large language models (LLMs) become default tools for online information verification, an implicit assumption follows them: that scale and general capability are sufficient for nuanced classification of misinformation discourse. We test this assumption directly on 900 Reddit comments spanning three PolitiFact-verified misinformation claims (environment, health, immigration), labelled as belief (propagates the claim), fact-check (corrects it), or other. We compare nine models across three paradigms -- BART-MNLI, three Llama variants, three commercial frontier LLMs (Claude Haiku 4.5, Gemini Flash Lite 2.5, Claude Sonnet 4.6), and fine-tuned DistilBERT and RoBERTa -- under universal and topic-specific label schemas. The assumption does not hold. Fine-tuned RoBERTa reaches 0.62 macro-$F_1$ against a best zero-shot result of 0.50 (Claude Haiku 4.5), at a fraction of the per-query cost; the supervised advantage is concentrated on the belief class, the implicit, affective category every zero-shot model under-detects. Scaling does not help: Llama-3-8B matches Llama-3-70B, and Claude Sonnet 4.6 underperforms the smaller Haiku under generic labels, collapsing belief detection to 0.17 and refusing outright on a subset of comments flagged as sensitive. This is a safety-alignment artefact, not a capacity limit. Label schema and topic jointly shape zero-shot performance, with the same model varying by more than 0.13 macro-$F_1$ across topics under matched labels. In a verification context, where missing belief is the costlier error, task-specific fine-tuning remains the more reliable choice despite the proliferation of large generative models.

IVMar 6, 2022
Fluid registration between lung CT and stationary chest tomosynthesis images

Lin Tian, Connor Puett, Peirong Liu et al. · harvard

Registration is widely used in image-guided therapy and image-guided surgery to estimate spatial correspondences between organs of interest between planning and treatment images. However, while high-quality computed tomography (CT) images are often available at planning time, limited angle acquisitions are frequently used during treatment because of radiation concerns or imaging time constraints. This requires algorithms to register CT images based on limited angle acquisitions. We, therefore, formulate a 3D/2D registration approach which infers a 3D deformation based on measured projections and digitally reconstructed radiographs of the CT. Most 3D/2D registration approaches use simple transformation models or require complex mathematical derivations to formulate the underlying optimization problem. Instead, our approach entirely relies on differentiable operations which can be combined with modern computational toolboxes supporting automatic differentiation. This then allows for rapid prototyping, integration with deep neural networks, and to support a variety of transformation models including fluid flow models. We demonstrate our approach for the registration between CT and stationary chest tomosynthesis (sDCT) images and show how it naturally leads to an iterative image reconstruction approach.

SIFeb 2Code
DREAMS: A Social Exchange Theory-Informed Modeling of Misinformation Engagement on Social Media

Lin Tian, Marian-Andrei Rizoiu

Social media engagement prediction is a central challenge in computational social science, particularly for understanding how users interact with misinformation. Existing approaches often treat engagement as a homogeneous time-series signal, overlooking the heterogeneous social mechanisms and platform designs that shape how misinformation spreads. In this work, we ask: ``Can neural architectures discover social exchange principles from behavioral data alone?'' We introduce \textsc{Dreams} (\underline{D}isentangled \underline{R}epresentations and \underline{E}pisodic \underline{A}daptive \underline{M}odeling for \underline{S}ocial media misinformation engagements), a social exchange theory-guided framework that models misinformation engagement as a dynamic process of social exchange. Rather than treating engagement as a static outcome, \textsc{Dreams} models it as a sequence-to-sequence adaptation problem, where each action reflects an evolving negotiation between user effort and social reward conditioned by platform context. It integrates adaptive mechanisms to learn how emotional and contextual signals propagate through time and across platforms. On a cross-platform dataset spanning $7$ platforms and 2.37M posts collected between 2021 and 2025, \textsc{Dreams} achieves state-of-the-art performance in predicting misinformation engagements, reaching a mean absolute percentage error of $19.25$\%. This is a $43.6$\% improvement over the strongest baseline. Beyond predictive gains, the model reveals consistent cross-platform patterns that align with social exchange principles, suggesting that integrating behavioral theory can enhance empirical modeling of online misinformation engagement. The source code is available at: https://github.com/ltian678/DREAMS.

CLJun 7, 2023
Examining Bias in Opinion Summarisation Through the Perspective of Opinion Diversity

Nannan Huang, Lin Tian, Haytham Fayek et al.

Opinion summarisation is a task that aims to condense the information presented in the source documents while retaining the core message and opinions. A summary that only represents the majority opinions will leave the minority opinions unrepresented in the summary. In this paper, we use the stance towards a certain target as an opinion. We study bias in opinion summarisation from the perspective of opinion diversity, which measures whether the model generated summary can cover a diverse set of opinions. In addition, we examine opinion similarity, a measure of how closely related two opinions are in terms of their stance on a given topic, and its relationship with opinion diversity. Through the lens of stances towards a topic, we examine opinion diversity and similarity using three debatable topics under COVID-19. Experimental results on these topics revealed that a higher degree of similarity of opinions did not indicate good diversity or fairly cover the various opinions originally presented in the source documents. We found that BART and ChatGPT can better capture diverse opinions presented in the source documents.

CVMar 9, 2024Code
uniGradICON: A Foundation Model for Medical Image Registration

Lin Tian, Hastings Greer, Roland Kwitt et al. · harvard

Conventional medical image registration approaches directly optimize over the parameters of a transformation model. These approaches have been highly successful and are used generically for registrations of different anatomical regions. Recent deep registration networks are incredibly fast and accurate but are only trained for specific tasks. Hence, they are no longer generic registration approaches. We therefore propose uniGradICON, a first step toward a foundation model for registration providing 1) great performance \emph{across} multiple datasets which is not feasible for current learning-based registration methods, 2) zero-shot capabilities for new registration tasks suitable for different acquisitions, anatomical regions, and modalities compared to the training dataset, and 3) a strong initialization for finetuning on out-of-distribution registration tasks. UniGradICON unifies the speed and accuracy benefits of learning-based registration algorithms with the generic applicability of conventional non-deep-learning approaches. We extensively trained and evaluated uniGradICON on twelve different public datasets. Our code and the uniGradICON model are available at https://github.com/uncbiag/uniGradICON.

CLFeb 7, 2025Code
Before It's Too Late: A State Space Model for the Early Prediction of Misinformation and Disinformation Engagement

Lin Tian, Emily Booth, Francesco Bailo et al.

In today's digital age, conspiracies and information campaigns can emerge rapidly and erode social and democratic cohesion. While recent deep learning approaches have made progress in modeling engagement through language and propagation models, they struggle with irregularly sampled data and early trajectory assessment. We present IC-Mamba, a novel state space model that forecasts social media engagement by modeling interval-censored data with integrated temporal embeddings. Our model excels at predicting engagement patterns within the crucial first 15-30 minutes of posting (RMSE 0.118-0.143), enabling rapid assessment of content reach. By incorporating interval-censored modeling into the state space framework, IC-Mamba captures fine-grained temporal dynamics of engagement growth, achieving a 4.72% improvement over state-of-the-art across multiple engagement metrics (likes, shares, comments, and emojis). Our experiments demonstrate IC-Mamba's effectiveness in forecasting both post-level dynamics and broader narrative patterns (F1 0.508-0.751 for narrative-level predictions). The model maintains strong predictive performance across extended time horizons, successfully forecasting opinion-level engagement up to 28 days ahead using observation windows of 3-10 days. These capabilities enable earlier identification of potentially problematic content, providing crucial lead time for designing and implementing countermeasures. Code is available at: https://github.com/ltian678/ic-mamba. An interactive dashboard demonstrating our results is available at: https://ic-mamba.behavioral-ds.science.

IVMar 13, 2025Code
Reference-Free 3D Reconstruction of Brain Dissection Photographs with Machine Learning

Lin Tian, Sean I. Young, Jonathan Williams Ramirez et al. · harvard

Correlation of neuropathology with MRI has the potential to transfer microscopic signatures of pathology to invivo scans. Recently, a classical registration method has been proposed, to build these correlations from 3D reconstructed stacks of dissection photographs, which are routinely taken at brain banks. These photographs bypass the need for exvivo MRI, which is not widely accessible. However, this method requires a full stack of brain slabs and a reference mask (e.g., acquired with a surface scanner), which severely limits the applicability of the technique. Here we propose RefFree, a dissection photograph reconstruction method without external reference. RefFree is a learning approach that estimates the 3D coordinates in the atlas space for every pixel in every photograph; simple least-squares fitting can then be used to compute the 3D reconstruction. As a by-product, RefFree also produces an atlas-based segmentation of the reconstructed stack. RefFree is trained on synthetic photographs generated from digitally sliced 3D MRI data, with randomized appearance for enhanced generalization ability. Experiments on simulated and real data show that RefFree achieves performance comparable to the baseline method without an explicit reference while also enabling reconstruction of partial stacks. Our code is available at https://github.com/lintian-a/reffree.

AISep 8, 2025Code
Tree of Agents: Improving Long-Context Capabilities of Large Language Models through Multi-Perspective Reasoning

Song Yu, Xiaofei Xu, Ke Deng et al.

Large language models (LLMs) face persistent challenges when handling long-context tasks, most notably the lost in the middle issue, where information located in the middle of a long input tends to be underutilized. Some existing methods that reduce input have the risk of discarding key information, while others that extend context windows often lead to attention dispersion. To address these limitations, we propose Tree of Agents (TOA), a multi-agent reasoning framework that segments the input into chunks processed by independent agents. Each agent generates its local cognition, then agents dynamically exchange information for collaborative reasoning along tree-structured paths. TOA enables agents to probe different reasoning orders for multi-perspective understanding, effectively mitigating position bias and reducing hallucinations. To improve processing efficiency, we incorporate prefix-hash caching and adaptive pruning strategies, achieving significant performance improvements with comparable API overhead. Experiments show that TOA, powered by compact LLaMA3.1-8B, significantly outperforms multiple baselines and demonstrates comparable performance to the latest and much larger commercial models, such as Gemini1.5-pro, on various long-context tasks. Code is available at https://github.com/Aireduce952/Tree-of-Agents.

CLAug 22, 2025Code
X-Troll: eXplainable Detection of State-Sponsored Information Operations Agents

Lin Tian, Xiuzhen Zhang, Maria Myung-Hee Kim et al.

State-sponsored trolls, malicious actors who deploy sophisticated linguistic manipulation in coordinated information campaigns, posing threats to online discourse integrity. While Large Language Models (LLMs) achieve strong performance on general natural language processing (NLP) tasks, they struggle with subtle propaganda detection and operate as ``black boxes'', providing no interpretable insights into manipulation strategies. This paper introduces X-Troll, a novel framework that bridges this gap by integrating explainable adapter-based LLMs with expert-derived linguistic knowledge to detect state-sponsored trolls and provide human-readable explanations for its decisions. X-Troll incorporates appraisal theory and propaganda analysis through specialized LoRA adapters, using dynamic gating to capture campaign-specific discourse patterns in coordinated information operations. Experiments on real-world data demonstrate that our linguistically-informed approach shows strong performance compared with both general LLM baselines and existing troll detection models in accuracy while providing enhanced transparency through expert-grounded explanations that reveal the specific linguistic strategies used by state-sponsored actors. X-Troll source code is available at: https://github.com/ltian678/xtroll_source/.

CLFeb 13, 2024Code
CMA-R:Causal Mediation Analysis for Explaining Rumour Detection

Lin Tian, Xiuzhen Zhang, Jey Han Lau

We apply causal mediation analysis to explain the decision-making process of neural models for rumour detection on Twitter. Interventions at the input and network level reveal the causal impacts of tweets and words in the model output. We find that our approach CMA-R -- Causal Mediation Analysis for Rumour detection -- identifies salient tweets that explain model predictions and show strong agreement with human judgements for critical tweets determining the truthfulness of stories. CMA-R can further highlight causally impactful words in the salient tweets, providing another layer of interpretability and transparency into these blackbox rumour detection systems. Code is available at: https://github.com/ltian678/cma-r.

CLJul 15, 2025
Mario at EXIST 2025: A Simple Gateway to Effective Multilingual Sexism Detection

Lin Tian, Johanne R. Trippas, Marian-Andrei Rizoiu

This paper presents our approach to EXIST 2025 Task 1, addressing text-based sexism detection in English and Spanish tweets through hierarchical Low-Rank Adaptation (LoRA) of Llama 3.1 8B. Our method introduces conditional adapter routing that explicitly models label dependencies across three hierarchically structured subtasks: binary sexism identification, source intention detection, and multilabel sexism categorization. Unlike conventional LoRA applications that target only attention layers, we apply adaptation to all linear transformations, enhancing the model's capacity to capture task-specific patterns. In contrast to complex data processing and ensemble approaches, we show that straightforward parameter-efficient fine-tuning achieves strong performance. We train separate LoRA adapters (rank=16, QLoRA 4-bit) for each subtask using unified multilingual training that leverages Llama 3.1's native bilingual capabilities. The method requires minimal preprocessing and uses standard supervised learning. Our multilingual training strategy eliminates the need for separate language-specific models, achieving 1.7-2.4\% F1 improvements through cross-lingual transfer. With only 1.67\% trainable parameters compared to full fine-tuning, our approach reduces training time by 75\% and model storage by 98\%, while achieving competitive performance across all subtasks (ICM-Hard: 0.6774 for binary classification, 0.4991 for intention detection, 0.6519 for multilabel categorization).

CLMay 25, 2025
Estimating Online Influence Needs Causal Modeling! Counterfactual Analysis of Social Media Engagement

Lin Tian, Marian-Andrei Rizoiu

Understanding true influence in social media requires distinguishing correlation from causation--particularly when analyzing misinformation spread. While existing approaches focus on exposure metrics and network structures, they often fail to capture the causal mechanisms by which external temporal signals trigger engagement. We introduce a novel joint treatment-outcome framework that leverages existing sequential models to simultaneously adapt to both policy timing and engagement effects. Our approach adapts causal inference techniques from healthcare to estimate Average Treatment Effects (ATE) within the sequential nature of social media interactions, tackling challenges from external confounding signals. Through our experiments on real-world misinformation and disinformation datasets, we show that our models outperform existing benchmarks by 15--22% in predicting engagement across diverse counterfactual scenarios, including exposure adjustment, timing shifts, and varied intervention durations. Case studies on 492 social media users show our causal effect measure aligns strongly with the gold standard in influence estimation, the expert-based empirical influence.

AIOct 22, 2025
Learning to Make Friends: Coaching LLM Agents toward Emergent Social Ties

Philipp J. Schneider, Lin Tian, Marian-Andrei Rizoiu

Can large language model (LLM) agents reproduce the complex social dynamics that characterize human online behavior -- shaped by homophily, reciprocity, and social validation -- and what memory and learning mechanisms enable such dynamics to emerge? We present a multi-agent LLM simulation framework in which agents repeatedly interact, evaluate one another, and adapt their behavior through in-context learning accelerated by a coaching signal. To model human social behavior, we design behavioral reward functions that capture core drivers of online engagement, including social interaction, information seeking, self-presentation, coordination, and emotional support. These rewards align agent objectives with empirically observed user motivations, enabling the study of how network structures and group formations emerge from individual decision-making. Our experiments show that coached LLM agents develop stable interaction patterns and form emergent social ties, yielding network structures that mirror properties of real online communities. By combining behavioral rewards with in-context adaptation, our framework establishes a principled testbed for investigating collective dynamics in LLM populations and reveals how artificial agents may approximate or diverge from human-like social behavior.

CVSep 27, 2025
Test-time Uncertainty Estimation for Medical Image Registration via Transformation Equivariance

Lin Tian, Xiaoling Hu, Juan Eugenio Iglesias · harvard

Accurate image registration is essential for downstream applications, yet current deep registration networks provide limited indications of whether and when their predictions are reliable. Existing uncertainty estimation strategies, such as Bayesian methods, ensembles, or MC dropout, require architectural changes or retraining, limiting their applicability to pretrained registration networks. Instead, we propose a test-time uncertainty estimation framework that is compatible with any pretrained networks. Our framework is grounded in the transformation equivariance property of registration, which states that the true mapping between two images should remain consistent under spatial perturbations of the input. By analyzing the variance of network predictions under such perturbations, we derive a theoretical decomposition of perturbation-based uncertainty in registration. This decomposition separates into two terms: (i) an intrinsic spread, reflecting epistemic noise, and (ii) a bias jitter, capturing how systematic error drifts under perturbations. Across four anatomical structures (brain, cardiac, abdominal, and lung) and multiple registration models (uniGradICON, SynthMorph), the uncertainty maps correlate consistently with registration errors and highlight regions requiring caution. Our framework turns any pretrained registration network into a risk-aware tool at test time, placing medical image registration one step closer to safe deployment in clinical and large-scale research settings.

CLMay 10, 2025
Signals from the Floods: AI-Driven Disaster Analysis through Multi-Source Data Fusion

Xian Gong, Paul X. McCarthy, Lin Tian et al.

Massive and diverse web data are increasingly vital for government disaster response, as demonstrated by the 2022 floods in New South Wales (NSW), Australia. This study examines how X (formerly Twitter) and public inquiry submissions provide insights into public behaviour during crises. We analyse more than 55,000 flood-related tweets and 1,450 submissions to identify behavioural patterns during extreme weather events. While social media posts are short and fragmented, inquiry submissions are detailed, multi-page documents offering structured insights. Our methodology integrates Latent Dirichlet Allocation (LDA) for topic modelling with Large Language Models (LLMs) to enhance semantic understanding. LDA reveals distinct opinions and geographic patterns, while LLMs improve filtering by identifying flood-relevant tweets using public submissions as a reference. This Relevance Index method reduces noise and prioritizes actionable content, improving situational awareness for emergency responders. By combining these complementary data streams, our approach introduces a novel AI-driven method to refine crisis-related social media content, improve real-time disaster response, and inform long-term resilience planning.

IVDec 13, 2021
The Brain Tumor Sequence Registration (BraTS-Reg) Challenge: Establishing Correspondence Between Pre-Operative and Follow-up MRI Scans of Diffuse Glioma Patients

Bhakti Baheti, Satrajit Chakrabarty, Hamed Akbari et al.

Registration of longitudinal brain MRI scans containing pathologies is challenging due to dramatic changes in tissue appearance. Although there has been progress in developing general-purpose medical image registration techniques, they have not yet attained the requisite precision and reliability for this task, highlighting its inherent complexity. Here we describe the Brain Tumor Sequence Registration (BraTS-Reg) challenge, as the first public benchmark environment for deformable registration algorithms focusing on estimating correspondences between pre-operative and follow-up scans of the same patient diagnosed with a diffuse brain glioma. The BraTS-Reg data comprise de-identified multi-institutional multi-parametric MRI (mpMRI) scans, curated for size and resolution according to a canonical anatomical template, and divided into training, validation, and testing sets. Clinical experts annotated ground truth (GT) landmark points of anatomical locations distinct across the temporal domain. Quantitative evaluation and ranking were based on the Median Euclidean Error (MEE), Robustness, and the determinant of the Jacobian of the displacement field. The top-ranked methodologies yielded similar performance across all evaluation metrics and shared several methodological commonalities, including pre-alignment, deep neural networks, inverse consistency analysis, and test-time instance optimization per-case basis as a post-processing step. The top-ranked method attained the MEE at or below that of the inter-rater variability for approximately 60% of the evaluated landmarks, underscoring the scope for further accuracy and robustness improvements, especially relative to human experts. The aim of BraTS-Reg is to continue to serve as an active resource for research, with the data and online evaluation tools accessible at https://bratsreg.github.io/.

CLSep 27, 2021
Rumour Detection via Zero-shot Cross-lingual Transfer Learning

Lin Tian, Xiuzhen Zhang, Jey Han Lau

Most rumour detection models for social media are designed for one specific language (mostly English). There are over 40 languages on Twitter and most languages lack annotated resources to build rumour detection models. In this paper we propose a zero-shot cross-lingual transfer learning framework that can adapt a rumour detection model trained for a source language to another target language. Our framework utilises pretrained multilingual language models (e.g.\ multilingual BERT) and a self-training loop to iteratively bootstrap the creation of ''silver labels'' in the target language to adapt the model from the source language to the target language. We evaluate our methodology on English and Chinese rumour datasets and demonstrate that our model substantially outperforms competitive benchmarks in both source and target language rumour detection.

IVNov 24, 2020
Discovering Hidden Physics Behind Transport Dynamics

Peirong Liu, Lin Tian, Yubo Zhang et al.

Transport processes are ubiquitous. They are, for example, at the heart of optical flow approaches; or of perfusion imaging, where blood transport is assessed, most commonly by injecting a tracer. An advection-diffusion equation is widely used to describe these transport phenomena. Our goal is estimating the underlying physics of advection-diffusion equations, expressed as velocity and diffusion tensor fields. We propose a learning framework (YETI) building on an auto-encoder structure between 2D and 3D image time-series, which incorporates the advection-diffusion model. To help with identifiability, we develop an advection-diffusion simulator which allows pre-training of our model by supervised learning using the velocity and diffusion tensor fields. Instead of directly learning these velocity and diffusion tensor fields, we introduce representations that assure incompressible flow and symmetric positive semi-definite diffusion fields and demonstrate the additional benefits of these representations on improving estimation accuracy. We further use transfer learning to apply YETI on a public brain magnetic resonance (MR) perfusion dataset of stroke patients and show its ability to successfully distinguish stroke lesions from normal brain regions via the estimated velocity and diffusion tensor fields.