Fast-DDPM: Fast Denoising Diffusion Probabilistic Models for Medical Image-to-Image GenerationHongxu Jiang, Muhammad Imran, Teng Zhang et al.
Denoising diffusion probabilistic models (DDPMs) have achieved unprecedented success in computer vision. However, they remain underutilized in medical imaging, a field crucial for disease diagnosis and treatment planning. This is primarily due to the high computational cost associated with (1) the use of large number of time steps (e.g., 1,000) in diffusion processes and (2) the increased dimensionality of medical images, which are often 3D or 4D. Training a diffusion model on medical images typically takes days to weeks, while sampling each image volume takes minutes to hours. To address this challenge, we introduce Fast-DDPM, a simple yet effective approach capable of improving training speed, sampling speed, and generation quality simultaneously. Unlike DDPM, which trains the image denoiser across 1,000 time steps, Fast-DDPM trains and samples using only 10 time steps. The key to our method lies in aligning the training and sampling procedures to optimize time-step utilization. Specifically, we introduced two efficient noise schedulers with 10 time steps: one with uniform time step sampling and another with non-uniform sampling. We evaluated Fast-DDPM across three medical image-to-image generation tasks: multi-image super-resolution, image denoising, and image-to-image translation. Fast-DDPM outperformed DDPM and current state-of-the-art methods based on convolutional networks and generative adversarial networks in all tasks. Additionally, Fast-DDPM reduced the training time to 0.2x and the sampling time to 0.01x compared to DDPM. Our code is publicly available at: https://github.com/mirthAI/Fast-DDPM.
29.6LGFeb 14, 2025
Ten Challenging Problems in Federated Foundation ModelsTao Fan, Hanlin Gu, Xuemei Cao et al.
Federated Foundation Models (FedFMs) represent a distributed learning paradigm that fuses general competences of foundation models as well as privacy-preserving capabilities of federated learning. This combination allows the large foundation models and the small local domain models at the remote clients to learn from each other in a teacher-student learning setting. This paper provides a comprehensive summary of the ten challenging problems inherent in FedFMs, encompassing foundational theory, utilization of private data, continual learning, unlearning, Non-IID and graph data, bidirectional knowledge transfer, incentive mechanism design, game mechanism design, model watermarking, and efficiency. The ten challenging problems manifest in five pivotal aspects: ``Foundational Theory," which aims to establish a coherent and unifying theoretical framework for FedFMs. ``Data," addressing the difficulties in leveraging domain-specific knowledge from private data while maintaining privacy; ``Heterogeneity," examining variations in data, model, and computational resources across clients; ``Security and Privacy," focusing on defenses against malicious attacks and model theft; and ``Efficiency," highlighting the need for improvements in training, communication, and parameter efficiency. For each problem, we offer a clear mathematical definition on the objective function, analyze existing methods, and discuss the key challenges and potential solutions. This in-depth exploration aims to advance the theoretical foundations of FedFMs, guide practical implementations, and inspire future research to overcome these obstacles, thereby enabling the robust, efficient, and privacy-preserving FedFMs in various real-world applications.
3.3AINov 25, 2025
RPM-MCTS: Knowledge-Retrieval as Process Reward Model with Monte Carlo Tree Search for Code GenerationYuanyuan Lin, Xiangyu Ouyang, Teng Zhang et al.
Tree search-based methods have made significant progress in enhancing the code generation capabilities of large language models. However, due to the difficulty in effectively evaluating intermediate algorithmic steps and the inability to locate and timely correct erroneous steps, these methods often generate incorrect code and incur increased computational costs. To tackle these problems, we propose RPM-MCTS, an effective method that utilizes Knowledge-Retrieval as Process Reward Model based on Monte Carlo Tree Search to evaluate intermediate algorithmic steps. By utilizing knowledge base retrieval, RPM-MCTS avoids the complex training of process reward models. During the expansion phase, similarity filtering is employed to remove redundant nodes, ensuring diversity in reasoning paths. Furthermore, our method utilizes sandbox execution feedback to locate erroneous algorithmic steps during generation, enabling timely and targeted corrections. Extensive experiments on four public code generation benchmarks demonstrate that RPM-MCTS outperforms current state-of-the-art methods while achieving an approximately 15% reduction in token consumption. Furthermore, full fine-tuning of the base model using the data constructed by RPM-MCTS significantly enhances its code capabilities.