Yu Wang

Ruize Zhang, Zelai Xu, Chengdong Ma et al. · tsinghua

Self-play, a learning paradigm where agents iteratively refine their policies by interacting with historical or concurrent versions of themselves or other evolving agents, has shown remarkable success in solving complex non-cooperative multi-agent tasks. Despite its growing prominence in multi-agent reinforcement learning (MARL), such as Go, poker, and video games, a comprehensive and structured understanding of self-play remains lacking. This survey fills this gap by offering a comprehensive roadmap to the diverse landscape of self-play methods. We begin by introducing the necessary preliminaries, including the MARL framework and basic game theory concepts. Then, it provides a unified framework and classifies existing self-play algorithms within this framework. Moreover, the paper bridges the gap between the algorithms and their practical implications by illustrating the role of self-play in different non-cooperative scenarios. Finally, the survey highlights open challenges and future research directions in self-play.

Ruochi Zhang, Haoran Wu, Yuting Xiu et al.

In recent years, the scientific community has become increasingly interested on peptides with non-canonical amino acids due to their superior stability and resistance to proteolytic degradation. These peptides present promising modifications to biological, pharmacological, and physiochemical attributes in both endogenous and engineered peptides. Notwithstanding their considerable advantages, the scientific community exhibits a conspicuous absence of an effective pre-trained model adept at distilling feature representations from such complex peptide sequences. We herein propose PepLand, a novel pre-training architecture for representation and property analysis of peptides spanning both canonical and non-canonical amino acids. In essence, PepLand leverages a comprehensive multi-view heterogeneous graph neural network tailored to unveil the subtle structural representations of peptides. Empirical validations underscore PepLand's effectiveness across an array of peptide property predictions, encompassing protein-protein interactions, permeability, solubility, and synthesizability. The rigorous evaluation confirms PepLand's unparalleled capability in capturing salient synthetic peptide features, thereby laying a robust foundation for transformative advances in peptide-centric research domains. We have made all the source code utilized in this study publicly accessible via GitHub at https://github.com/zhangruochi/pepland

Xinyi Yang, Yuxiang Yang, Chao Yu et al.

This paper investigates the multi-agent cooperative exploration problem, which requires multiple agents to explore an unseen environment via sensory signals in a limited time. A popular approach to exploration tasks is to combine active mapping with planning. Metric maps capture the details of the spatial representation, but are with high communication traffic and may vary significantly between scenarios, resulting in inferior generalization. Topological maps are a promising alternative as they consist only of nodes and edges with abstract but essential information and are less influenced by the scene structures. However, most existing topology-based exploration tasks utilize classical methods for planning, which are time-consuming and sub-optimal due to their handcrafted design. Deep reinforcement learning (DRL) has shown great potential for learning (near) optimal policies through fast end-to-end inference. In this paper, we propose Multi-Agent Neural Topological Mapping (MANTM) to improve exploration efficiency and generalization for multi-agent exploration tasks. MANTM mainly comprises a Topological Mapper and a novel RL-based Hierarchical Topological Planner (HTP). The Topological Mapper employs a visual encoder and distance-based heuristics to construct a graph containing main nodes and their corresponding ghost nodes. The HTP leverages graph neural networks to capture correlations between agents and graph nodes in a coarse-to-fine manner for effective global goal selection. Extensive experiments conducted in a physically-realistic simulator, Habitat, demonstrate that MANTM reduces the steps by at least 26.40% over planning-based baselines and by at least 7.63% over RL-based competitors in unseen scenarios.

Junda Wu, Yuxin Xiong, Xintong Li et al.

Recent MLLMs have shown emerging visual understanding and reasoning abilities after being pre-trained on large-scale multimodal datasets. Unlike pre-training, where MLLMs receive rich visual-text alignment, instruction-tuning is often text-driven with weaker visual supervision, leading to the degradation of pre-trained visual understanding and causing visual forgetting. Existing approaches, such as direct fine-tuning and continual learning methods, fail to explicitly address this issue, often compressing visual representations and prioritizing task alignment over visual retention, which further worsens visual forgetting. To overcome this limitation, we introduce a novel perspective leveraging effective rank to quantify the degradation of visual representation richness, interpreting this degradation through the information bottleneck principle as excessive compression that leads to the degradation of crucial pre-trained visual knowledge. Building on this view, we propose a modality-decoupled gradient descent (MDGD) method that regulates gradient updates to maintain the effective rank of visual representations while mitigating the over-compression effects described by the information bottleneck. By explicitly disentangling the optimization of visual understanding from task-specific alignment, MDGD preserves pre-trained visual knowledge while enabling efficient task adaptation. To enable lightweight instruction-tuning, we further develop a memory-efficient fine-tuning approach using gradient masking, which selectively updates a subset of model parameters to enable parameter-efficient fine-tuning (PEFT), reducing computational overhead while preserving rich visual representations. Extensive experiments across various downstream tasks and backbone MLLMs demonstrate that MDGD effectively mitigates visual forgetting from pre-trained tasks while enabling strong adaptation to new tasks.

Ruize Zhang, Sirui Xiang, Zelai Xu et al. · tsinghua

In this paper, we tackle the problem of learning to play 3v3 multi-drone volleyball, a new embodied competitive task that requires both high-level strategic coordination and low-level agile control. The task is turn-based, multi-agent, and physically grounded, posing significant challenges due to its long-horizon dependencies, tight inter-agent coupling, and the underactuated dynamics of quadrotors. To address this, we propose Hierarchical Co-Self-Play (HCSP), a hierarchical reinforcement learning framework that separates centralized high-level strategic decision-making from decentralized low-level motion control. We design a three-stage population-based training pipeline to enable both strategy and skill to emerge from scratch without expert demonstrations: (I) training diverse low-level skills, (II) learning high-level strategy via self-play with fixed low-level skills, and (III) joint fine-tuning through co-self-play. Experiments show that HCSP achieves superior performance, outperforming non-hierarchical self-play and rule-based hierarchical baselines with an average 82.9% win rate and a 71.5% win rate against the two-stage variant. Moreover, co-self-play leads to emergent team behaviors such as role switching and coordinated formations, demonstrating the effectiveness of our hierarchical design and training scheme. The project page is at https://sites.google.com/view/hi-co-self-play.