Lei Wu

Sicheng Zhou, Lei Wu, Cao Xiao et al.

Self-supervised learning (SSL) has transformed vision encoder training in general domains but remains underutilized in medical imaging due to limited data and domain specific biases. We present MammoDINO, a novel SSL framework for mammography, pretrained on 1.4 million mammographic images. To capture clinically meaningful features, we introduce a breast tissue aware data augmentation sampler for both image-level and patch-level supervision and a cross-slice contrastive learning objective that leverages 3D digital breast tomosynthesis (DBT) structure into 2D pretraining. MammoDINO achieves state-of-the-art performance on multiple breast cancer screening tasks and generalizes well across five benchmark datasets. It offers a scalable, annotation-free foundation for multipurpose computer-aided diagnosis (CAD) tools for mammogram, helping reduce radiologists' workload and improve diagnostic efficiency in breast cancer screening.

Zhijian Yang, Noel DSouza, Istvan Megyeri et al.

Magnetic Resonance Imaging (MRI) is a critical medical imaging modality in clinical diagnosis and research, yet its complexity and heterogeneity pose challenges for automated analysis, particularly in scalable and generalizable machine learning applications. While foundation models have revolutionized natural language and vision tasks, their application to MRI remains limited due to data scarcity and narrow anatomical focus. In this work, we present Decipher-MR, a 3D MRI-specific vision-language foundation model trained on a large-scale dataset comprising 200,000 MRI series from over 22,000 studies spanning diverse anatomical regions, sequences, and pathologies. Decipher-MR integrates self-supervised vision learning with report-guided text supervision to build robust, generalizable representations, enabling effective adaptation across broad applications. To enable robust and diverse clinical tasks with minimal computational overhead, Decipher-MR supports a modular design that enables tuning of lightweight, task-specific decoders attached to a frozen pretrained encoder. Following this setting, we evaluate Decipher-MR across diverse benchmarks including disease classification, demographic prediction, anatomical localization, and cross-modal retrieval, demonstrating consistent performance gains over existing foundation models and task-specific approaches. Our results establish Decipher-MR as a scalable and versatile foundation for MRI-based AI, facilitating efficient development across clinical and research domains.

Jiebin Yan, Ziwen Tan, Jiale Rao et al.

Blind panoramic image quality assessment (BPIQA) has recently brought new challenge to the visual quality community, due to the complex interaction between immersive content and human behavior. Although many efforts have been made to advance BPIQA from both conducting psychophysical experiments and designing performance-driven objective algorithms, \textit{limited content} and \textit{few samples} in those closed sets inevitably would result in shaky conclusions, thereby hindering the development of BPIQA, we refer to it as the \textit{easy-database} issue. In this paper, we present a sufficient computational analysis of degradation modeling in BPIQA to thoroughly explore the \textit{easy-database issue}, where we carefully design three types of experiments via investigating the gap between BPIQA and blind image quality assessment (BIQA), the necessity of specific design in BPIQA models, and the generalization ability of BPIQA models. From extensive experiments, we find that easy databases narrow the gap between the performance of BPIQA and BIQA models, which is unconducive to the development of BPIQA. And the easy databases make the BPIQA models be closed to saturation, therefore the effectiveness of the associated specific designs can not be well verified. Besides, the BPIQA models trained on our recently proposed databases with complicated degradation show better generalization ability. Thus, we believe that much more efforts are highly desired to put into BPIQA from both subjective viewpoint and objective viewpoint.