CVAIOct 13, 2025

MammoDINO: Anatomically Aware Self-Supervision for Mammographic Images

arXiv:2510.11883v1h-index: 18
Originality Incremental advance
AI Analysis

This work addresses the need for scalable, annotation-free computer-aided diagnosis tools in mammography to reduce radiologists' workload and improve efficiency in breast cancer screening, representing a domain-specific advancement.

The authors tackled the problem of underutilized self-supervised learning in medical imaging by developing MammoDINO, a framework pretrained on 1.4 million mammographic images, which achieved state-of-the-art performance on multiple breast cancer screening tasks and generalized well across five benchmark datasets.

Self-supervised learning (SSL) has transformed vision encoder training in general domains but remains underutilized in medical imaging due to limited data and domain specific biases. We present MammoDINO, a novel SSL framework for mammography, pretrained on 1.4 million mammographic images. To capture clinically meaningful features, we introduce a breast tissue aware data augmentation sampler for both image-level and patch-level supervision and a cross-slice contrastive learning objective that leverages 3D digital breast tomosynthesis (DBT) structure into 2D pretraining. MammoDINO achieves state-of-the-art performance on multiple breast cancer screening tasks and generalizes well across five benchmark datasets. It offers a scalable, annotation-free foundation for multipurpose computer-aided diagnosis (CAD) tools for mammogram, helping reduce radiologists' workload and improve diagnostic efficiency in breast cancer screening.

Foundations

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