Ziqi Gao

Ziqi Gao, Weikai Huang, Jieyu Zhang et al.

Recent advances in text-to-vision generation excel in visual fidelity but struggle with compositional generalization and semantic alignment. Existing datasets are noisy and weakly compositional, limiting models' understanding of complex scenes, while scalable solutions for dense, high-quality annotations remain a challenge. We introduce Generate Any Scene, a data engine that systematically enumerates scene graphs representing the combinatorial array of possible visual scenes. Generate Any Scene dynamically constructs scene graphs of varying complexity from a structured taxonomy of objects, attributes, and relations. Given a sampled scene graph, Generate Any Scene translates it into a caption for text-to-image or text-to-video generation; it also translates it into a set of visual question answers that allow automatic evaluation and reward modeling of semantic alignment. Using Generate Any Scene, we first design a self-improving framework where models iteratively enhance their performance using generated data. Stable Diffusion v1.5 achieves an average 4% improvement over baselines and surpassing fine-tuning on CC3M. Second, we also design a distillation algorithm to transfer specific strengths from proprietary models to their open-source counterparts. Using fewer than 800 synthetic captions, we fine-tune Stable Diffusion v1.5 and achieve a 10% increase in TIFA score on compositional and hard concept generation. Third, we create a reward model to align model generation with semantic accuracy at a low cost. Using GRPO algorithm, we fine-tune SimpleAR-0.5B-SFT and surpass CLIP-based methods by +5% on DPG-Bench. Finally, we apply these ideas to the downstream task of content moderation where we train models to identify challenging cases by learning from synthetic data.

Guanlue Li, Chenran Jiang, Ziqi Gao et al.

Effective generation of molecular structures, or new chemical entities, that bind to target proteins is crucial for lead identification and optimization in drug discovery. Despite advancements in atom- and motif-wise deep learning models for 3D molecular generation, current methods often struggle with validity and reliability. To address these issues, we develop the Atom-Motif Consistency Diffusion Model (AMDiff), utilizing a joint-training paradigm for multi-view learning. This model features a hierarchical diffusion architecture that integrates both atom- and motif-level views of molecules, allowing for comprehensive exploration of complementary information. By leveraging classifier-free guidance and incorporating binding site features as conditional inputs, AMDiff ensures robust molecule generation across diverse targets. Compared to existing approaches, AMDiff exhibits superior validity and novelty in generating molecules tailored to fit various protein pockets. Case studies targeting protein kinases, including Anaplastic Lymphoma Kinase (ALK) and Cyclin-dependent kinase 4 (CDK4), demonstrate the model's capability in structure-based de novo drug design. Overall, AMDiff bridges the gap between atom-view and motif-view drug discovery and speeds up the process of target-aware molecular generation.

Weikai Huang, Jieyu Zhang, Taoyang Jia et al.

Visual grouping -- operationalized through tasks such as instance segmentation, visual grounding, and object detection -- enables applications ranging from robotic perception to photo editing. These fundamental problems in computer vision are powered by large-scale, painstakingly annotated datasets. Despite their impact, these datasets are costly to build, biased in coverage, and difficult to scale. Synthetic datasets offer a promising alternative but struggle with flexibility, accuracy, and compositional diversity. We introduce Synthetic Object Compositions (SOC), an accurate and scalable data synthesis pipeline via a novel object-centric composition strategy. It composes high-quality synthetic object segments into new images using 3D geometric layout augmentation and camera configuration augmentation with generative harmonization and mask-area-weighted blending, yielding accurate and diverse masks, boxes, and referring expressions. Models trained on just 100K of our synthetic images outperform those trained on larger real datasets (GRIT 20M, V3Det 200K) and synthetic pipelines (Copy-Paste, X-Paste, SynGround, SegGen) by +24-36% -- achieving +10.9 AP on LVIS and +8.4 NAcc on gRefCOCO. Beyond the general open-vocabulary setup, SOC also enables controllable dataset construction for different use cases and boosts performance in both low-data and closed-vocabulary scenarios. Augmenting LVIS and COCO with synthetic object segments delivers strong performance across different real-data scales and yields even greater improvements under extremely limited real-data conditions, including +6.59 AP on a 1% COCO data setup. Furthermore, this controllability enables targeted data generation for intra-class referring, a diagnostic grounding task we propose that requires fine-grained attribute discrimination.

Aochuan Chen, Yifan Niu, Ziqi Gao et al.

The LifeTime Value (LTV) prediction, which endeavors to forecast the cumulative purchase contribution of a user to a particular item, remains a vital challenge that advertisers are keen to resolve. A precise LTV prediction system enhances the alignment of user interests with meticulously designed advertisements, thereby generating substantial profits for advertisers. Nonetheless, this issue is complicated by the paucity of data typically observed in real-world advertising scenarios. The purchase rate among registered users is often as critically low as 0.1%, resulting in a dataset where the majority of users make only several purchases. Consequently, there is insufficient supervisory signal for effectively training the LTV prediction model. An additional challenge emerges from the interdependencies among tasks with high correlation. It is a common practice to estimate a user's contribution to a game over a specified temporal interval. Varying the lengths of these intervals corresponds to distinct predictive tasks, which are highly correlated. For instance, predictions over a 7-day period are heavily reliant on forecasts made over a 3-day period, where exceptional cases can adversely affect the accuracy of both tasks. In order to comprehensively address the aforementioned challenges, we introduce an innovative framework denoted as Graph-Represented Pareto-Optimal LifeTime Value prediction (GRePO-LTV). Graph representation learning is initially employed to address the issue of data scarcity. Subsequently, Pareto-Optimization is utilized to manage the interdependence of prediction tasks.