Hui Yi Leong

Hui Yi Leong, Yi Fan Gao, Ji Shuai et al.

Scientific research indicates that for every hour spent in direct patient care, physicians spend nearly two additional hours on administrative tasks, particularly on electronic health records (EHRs) and desk work. This excessive administrative burden not only reduces the time available for patient care but also contributes to physician burnout and inefficiencies in healthcare delivery. To address these challenges, this study introduces MediGen, a fine-tuned large language model (LLM) designed to automate the generation of medical reports from medical dialogues. By leveraging state-of-the-art methodologies for fine-tuning open-source pretrained models, including LLaMA3-8B, MediGen achieves high accuracy in transcribing and summarizing clinical interactions. The fine-tuned LLaMA3-8B model demonstrated promising results, achieving a ROUGE score of 58% and a BERTScore-F1 of 72%, indicating its effectiveness in generating accurate and clinically relevant medical reports. These findings suggest that MediGen has the potential to significantly reduce the administrative workload on physicians, improving both healthcare efficiency and physician well-being.

Hui Yi Leong, Yi Fan Gao, Shuai Ji et al.

The increasing administrative burden of medical documentation, particularly through Electronic Health Records (EHR), significantly reduces the time available for direct patient care and contributes to physician burnout. To address this issue, we propose MediNotes, an advanced generative AI framework designed to automate the creation of SOAP (Subjective, Objective, Assessment, Plan) notes from medical conversations. MediNotes integrates Large Language Models (LLMs), Retrieval-Augmented Generation (RAG), and Automatic Speech Recognition (ASR) to capture and process both text and voice inputs in real time or from recorded audio, generating structured and contextually accurate medical notes. The framework also incorporates advanced techniques like Quantized Low-Rank Adaptation (QLoRA) and Parameter-Efficient Fine-Tuning (PEFT) for efficient model fine-tuning in resource-constrained environments. Additionally, MediNotes offers a query-based retrieval system, allowing healthcare providers and patients to access relevant medical information quickly and accurately. Evaluations using the ACI-BENCH dataset demonstrate that MediNotes significantly improves the accuracy, efficiency, and usability of automated medical documentation, offering a robust solution to reduce the administrative burden on healthcare professionals while improving the quality of clinical workflows.

Chengbo Sun, Hui Yi Leong, Lei Li

The manual creation of the "Impression" section in radiology reports is a primary driver of radiologist burnout. To address this challenge, we propose a coarse-to-fine framework that leverages open-source large language models (LLMs) to automatically generate and personalize impressions from clinical findings. The system first produces a draft impression and then refines it using machine learning and reinforcement learning from human feedback (RLHF) to align with individual radiologists' styles while ensuring factual accuracy. We fine-tune LLaMA and Mistral models on a large dataset of reports from the University of Chicago Medicine. Our approach is designed to significantly reduce administrative workload and improve reporting efficiency while maintaining high standards of clinical precision.

Hao Zhang, Bo Huang, Zhenjia Li et al.

Large Language Models (LLMs) have transformed both everyday life and scientific research. However, adapting LLMs from general-purpose models to specialized tasks remains challenging, particularly in resource-constrained environments. Low-Rank Adaptation (LoRA), a prominent method within Parameter-Efficient Fine-Tuning (PEFT), has emerged as a promising approach to LLMs by approximating model weight updates using low-rank decomposition. However, LoRA is limited by its uniform rank ( r ) allocation to each incremental matrix, and existing rank allocation techniques aimed at addressing this issue remain computationally inefficient, complex, and unstable, hindering practical applications. To address these limitations, we propose Sensitivity-LoRA, an efficient fine-tuning method that dynamically allocates ranks to weight matrices based on both their global and local sensitivities. It leverages the second-order derivatives (Hessian Matrix) of the loss function to effectively capture weight sensitivity, enabling optimal rank allocation with minimal computational overhead. Our experimental results have demonstrated robust effectiveness, efficiency and stability of Sensitivity-LoRA across diverse tasks and benchmarks.

Yuheng Li, Jiechao Gao, Wei Han et al.

Knowledge of the medical decision process, which can be modeled as medical decision trees (MDTs), is critical to building clinical decision support systems. However, current MDT construction methods rely heavily on time-consuming and laborious manual annotation. To address this challenge, we propose PI-LoRA (Path-Integrated LoRA), a novel low-rank adaptation method for automatically extracting MDTs from clinical guidelines and textbooks. We integrate gradient path information to capture synergistic effects between different modules, enabling more effective and reliable rank allocation. This framework ensures that the most critical modules receive appropriate rank allocations while less important ones are pruned, resulting in a more efficient and accurate model for extracting medical decision trees from clinical texts. Extensive experiments on medical guideline datasets demonstrate that our PI-LoRA method significantly outperforms existing parameter-efficient fine-tuning approaches for the Text2MDT task, achieving better accuracy with substantially reduced model complexity. The proposed method achieves state-of-the-art results while maintaining a lightweight architecture, making it particularly suitable for clinical decision support systems where computational resources may be limited.

Hui Yi Leong, Yuheng Li, Yuqing Wu et al.

Although large language models (LLMs) have revolutionized natural language processing capabilities, their practical implementation as autonomous multi-agent systems (MAS) for industrial problem-solving encounters persistent barriers. Conventional MAS architectures are fundamentally restricted by inflexible, hand-crafted graph topologies that lack contextual responsiveness, resulting in diminished efficacy across varied academic and commercial workloads. To surmount these constraints, we introduce AMAS, a paradigm-shifting framework that redefines LLM-based MAS through a novel dynamic graph designer. This component autonomously identifies task-specific optimal graph configurations via lightweight LLM adaptation, eliminating the reliance on monolithic, universally applied structural templates. Instead, AMAS exploits the intrinsic properties of individual inputs to intelligently direct query trajectories through task-optimized agent pathways. Rigorous validation across question answering, mathematical deduction, and code generation benchmarks confirms that AMAS systematically exceeds state-of-the-art single-agent and multi-agent approaches across diverse LLM architectures. Our investigation establishes that context-sensitive structural adaptability constitutes a foundational requirement for high-performance LLM MAS deployments.

Guancheng Wan, Lucheng Fu, Haoxin Liu et al.

The performance of Large Language Models (LLMs) hinges on carefully engineered prompts. However, prevailing prompt optimization methods, ranging from heuristic edits and reinforcement learning to evolutionary search, primarily target point-wise accuracy. They seldom enforce paraphrase invariance or searching stability, and therefore cannot remedy this brittleness in practice. Automated prompt search remains brittle: small, semantically preserving paraphrases often cause large performance swings. We identify this brittleness as the textual sharpness of the prompt landscape. In this work, we provide the first formal treatment of textual sharpness in the discrete, semantic space of prompts, together with an operational robustness criterion over a semantic neighborhood; the design is black-box or API-only, requiring no gradients to update the model's parameters. Then we introduce TARE (Textual Sharpness-Aware Evolving), a derivative-free framework that alternates between an inner, sampling-based adversarial search that stresses a prompt with hard paraphrases and an outer, robust selection that prefers candidates whose neighborhoods remain strong. We further propose ATARE, which learns anisotropic weights to shape the semantic neighborhood and adapts its radius over time to balance exploration and fidelity. Diverse tasks evaluate our methods, whose design for minimizing textual sharpness gap leads to prompts that preserve accuracy under paraphrasing, outperforming accuracy-only prompt search while remaining computationally practical.

Hui Yi Leong, Yuqing Wu

Current multi-agent systems (MAS) frameworks often rely on manually designed and static collaboration graph structures, limiting adaptability and performance. To address these limitations, we propose DynaSwarm, a dynamic framework that enhances LLM-based MAS through two key innovations: (1) an actor-critic reinforcement learning (A2C) mechanism to optimize graph structures with improved stability over prior RL methods, and (2) a dynamic graph selector that adaptively chooses the optimal graph structure for each input sample via parameter-efficient LLM fine-tuning. DynaSwarm eliminates the need for rigid, one-fits-all graph architectures, instead leveraging sample-specific idiosyncrasies to dynamically route queries through specialized agent networks. (c) We propose to fine-tune the demonstration retriever to fully exploit the power of in-context learning (ICL). Extensive experiments on question answering, mathematical reasoning, and coding tasks demonstrate that DynaSwarm consistently outperforms state-of-the-art single-agent and MAS baselines across multiple LLM backbones. Our findings highlight the importance of sample-aware structural flexibility in LLM MAS designs.