Xingyu Li

Hong Li, Xingyu Li, Pengbo Hu et al.

While the field of multi-modal learning keeps growing fast, the deficiency of the standard joint training paradigm has become clear through recent studies. They attribute the sub-optimal performance of the jointly trained model to the modality competition phenomenon. Existing works attempt to improve the jointly trained model by modulating the training process. Despite their effectiveness, those methods can only apply to late fusion models. More importantly, the mechanism of the modality competition remains unexplored. In this paper, we first propose an adaptive gradient modulation method that can boost the performance of multi-modal models with various fusion strategies. Extensive experiments show that our method surpasses all existing modulation methods. Furthermore, to have a quantitative understanding of the modality competition and the mechanism behind the effectiveness of our modulation method, we introduce a novel metric to measure the competition strength. This metric is built on the mono-modal concept, a function that is designed to represent the competition-less state of a modality. Through systematic investigation, our results confirm the intuition that the modulation encourages the model to rely on the more informative modality. In addition, we find that the jointly trained model typically has a preferred modality on which the competition is weaker than other modalities. However, this preferred modality need not dominate others. Our code will be available at https://github.com/lihong2303/AGM_ICCV2023.

Hao Quan, Xingyu Li, Weixing Chen et al.

Based on digital pathology slice scanning technology, artificial intelligence algorithms represented by deep learning have achieved remarkable results in the field of computational pathology. Compared to other medical images, pathology images are more difficult to annotate, and thus, there is an extreme lack of available datasets for conducting supervised learning to train robust deep learning models. In this paper, we propose a self-supervised learning (SSL) model, the global contrast-masked autoencoder (GCMAE), which can train the encoder to have the ability to represent local-global features of pathological images, also significantly improve the performance of transfer learning across data sets. In this study, the ability of the GCMAE to learn migratable representations was demonstrated through extensive experiments using a total of three different disease-specific hematoxylin and eosin (HE)-stained pathology datasets: Camelyon16, NCTCRC and BreakHis. In addition, this study designed an effective automated pathology diagnosis process based on the GCMAE for clinical applications. The source code of this paper is publicly available at https://github.com/StarUniversus/gcmae.

Jinan Bao, Hanshi Sun, Hanqiu Deng et al.

Anomaly detection (AD) is a fundamental research problem in machine learning and computer vision, with practical applications in industrial inspection, video surveillance, and medical diagnosis. In medical imaging, AD is especially vital for detecting and diagnosing anomalies that may indicate rare diseases or conditions. However, there is a lack of a universal and fair benchmark for evaluating AD methods on medical images, which hinders the development of more generalized and robust AD methods in this specific domain. To bridge this gap, we introduce a comprehensive evaluation benchmark for assessing anomaly detection methods on medical images. This benchmark encompasses six reorganized datasets from five medical domains (i.e. brain MRI, liver CT, retinal OCT, chest X-ray, and digital histopathology) and three key evaluation metrics, and includes a total of fourteen state-of-the-art AD algorithms. This standardized and well-curated medical benchmark with the well-structured codebase enables comprehensive comparisons among recently proposed anomaly detection methods. It will facilitate the community to conduct a fair comparison and advance the field of AD on medical imaging. More information on BMAD is available in our GitHub repository: https://github.com/DorisBao/BMAD

Xiaohan Zhang, Xingyu Li, Waqas Sultani et al.

Cross-view geo-localization aims to estimate the location of a query ground image by matching it to a reference geo-tagged aerial images database. As an extremely challenging task, its difficulties root in the drastic view changes and different capturing time between two views. Despite these difficulties, recent works achieve outstanding progress on cross-view geo-localization benchmarks. However, existing methods still suffer from poor performance on the cross-area benchmarks, in which the training and testing data are captured from two different regions. We attribute this deficiency to the lack of ability to extract the spatial configuration of visual feature layouts and models' overfitting on low-level details from the training set. In this paper, we propose GeoDTR which explicitly disentangles geometric information from raw features and learns the spatial correlations among visual features from aerial and ground pairs with a novel geometric layout extractor module. This module generates a set of geometric layout descriptors, modulating the raw features and producing high-quality latent representations. In addition, we elaborate on two categories of data augmentations, (i) Layout simulation, which varies the spatial configuration while keeping the low-level details intact. (ii) Semantic augmentation, which alters the low-level details and encourages the model to capture spatial configurations. These augmentations help to improve the performance of the cross-view geo-localization models, especially on the cross-area benchmarks. Moreover, we propose a counterfactual-based learning process to benefit the geometric layout extractor in exploring spatial information. Extensive experiments show that GeoDTR not only achieves state-of-the-art results but also significantly boosts the performance on same-area and cross-area benchmarks.

Xiaohan Zhang, Xingyu Li, Waqas Sultani et al.

Cross-View Geo-Localization (CVGL) estimates the location of a ground image by matching it to a geo-tagged aerial image in a database. Recent works achieve outstanding progress on CVGL benchmarks. However, existing methods still suffer from poor performance in cross-area evaluation, in which the training and testing data are captured from completely distinct areas. We attribute this deficiency to the lack of ability to extract the geometric layout of visual features and models' overfitting to low-level details. Our preliminary work introduced a Geometric Layout Extractor (GLE) to capture the geometric layout from input features. However, the previous GLE does not fully exploit information in the input feature. In this work, we propose GeoDTR+ with an enhanced GLE module that better models the correlations among visual features. To fully explore the LS techniques from our preliminary work, we further propose Contrastive Hard Samples Generation (CHSG) to facilitate model training. Extensive experiments show that GeoDTR+ achieves state-of-the-art (SOTA) results in cross-area evaluation on CVUSA, CVACT, and VIGOR by a large margin ($16.44\%$, $22.71\%$, and $13.66\%$ without polar transformation) while keeping the same-area performance comparable to existing SOTA. Moreover, we provide detailed analyses of GeoDTR+. Our code will be available at https://gitlab.com/vail-uvm/geodtr plus.

Pengbo Hu, Ji Qi, Xingyu Li et al.

There emerges a promising trend of using large language models (LLMs) to generate code-like plans for complex inference tasks such as visual reasoning. This paradigm, known as LLM-based planning, provides flexibility in problem solving and endows better interpretability. However, current research is mostly limited to basic scenarios of simple questions that can be straightforward answered in a few inference steps. Planning for the more challenging multi-hop visual reasoning tasks remains under-explored. Specifically, under multi-hop reasoning situations, the trade-off between accuracy and the complexity of plan-searching becomes prominent. The prevailing algorithms either address the efficiency issue by employing the fast one-stop generation or adopt a complex iterative generation method to improve accuracy. Both fail to balance the need for efficiency and performance. Drawing inspiration from the dual system of cognition in the human brain, the fast and the slow think processes, we propose a hierarchical plan-searching algorithm that integrates the one-stop reasoning (fast) and the Tree-of-thought (slow). Our approach succeeds in performance while significantly saving inference steps. Moreover, we repurpose the PTR and the CLEVER datasets, developing a systematic framework for evaluating the performance and efficiency of LLMs-based plan-search algorithms under reasoning tasks at different levels of difficulty. Extensive experiments demonstrate the superiority of our proposed algorithm in terms of performance and efficiency. The dataset and code will be release soon.

Nico Schiavone, Jingyi Wang, Shuangzhi Li et al.

Active Learning (AL) and Few Shot Learning (FSL) are two label-efficient methods which have achieved excellent results recently. However, most prior arts in both learning paradigms fail to explore the wealth of the vast unlabelled data. In this study, we address this issue in the scenario where the annotation budget is very limited, yet a large amount of unlabelled data for the target task is available. We frame this work in the context of histopathology where labelling is prohibitively expensive. To this end, we introduce an active few shot learning framework, Myriad Active Learning (MAL), including a contrastive-learning encoder, pseudo-label generation, and novel query sample selection in the loop. Specifically, we propose to massage unlabelled data in a self-supervised manner, where the obtained data representations and clustering knowledge form the basis to activate the AL loop. With feedback from the oracle in each AL cycle, the pseudo-labels of the unlabelled data are refined by optimizing a shallow task-specific net on top of the encoder. These updated pseudo-labels serve to inform and improve the active learning query selection process. Furthermore, we introduce a novel recipe to combine existing uncertainty measures and utilize the entire uncertainty list to reduce sample redundancy in AL. Extensive experiments on two public histopathology datasets show that MAL has superior test accuracy, macro F1-score, and label efficiency compared to prior works, and can achieve a comparable test accuracy to a fully supervised algorithm while labelling only 5% of the dataset.

Pengbo Hu, Xingyu Li, Yi Zhou

As deep learning advances, there is an ever-growing demand for models capable of synthesizing information from multi-modal resources to address the complex tasks raised from real-life applications. Recently, many large multi-modal datasets have been collected, on which researchers actively explore different methods of fusing multi-modal information. However, little attention has been paid to quantifying the contribution of different modalities within the proposed models. In this paper, we propose the {\bf SH}apley v{\bf A}lue-based {\bf PE}rceptual (SHAPE) scores that measure the marginal contribution of individual modalities and the degree of cooperation across modalities. Using these scores, we systematically evaluate different fusion methods on different multi-modal datasets for different tasks. Our experiments suggest that for some tasks where different modalities are complementary, the multi-modal models still tend to use the dominant modality alone and ignore the cooperation across modalities. On the other hand, models learn to exploit cross-modal cooperation when different modalities are indispensable for the task. In this case, the scores indicate it is better to fuse different modalities at relatively early stages. We hope our scores can help improve the understanding of how the present multi-modal models operate on different modalities and encourage more sophisticated methods of integrating multiple modalities.

Hanqiu Deng, Zhaoxiang Zhang, Jinan Bao et al.

Contrastive Language-Image Pre-training (CLIP) models have shown promising performance on zero-shot visual recognition tasks by learning visual representations under natural language supervision. Recent studies attempt the use of CLIP to tackle zero-shot anomaly detection by matching images with normal and abnormal state prompts. However, since CLIP focuses on building correspondence between paired text prompts and global image-level representations, the lack of fine-grained patch-level vision to text alignment limits its capability on precise visual anomaly localization. In this work, we propose AnoCLIP for zero-shot anomaly localization. In the visual encoder, we introduce a training-free value-wise attention mechanism to extract intrinsic local tokens of CLIP for patch-level local description. From the perspective of text supervision, we particularly design a unified domain-aware contrastive state prompting template for fine-grained vision-language matching. On top of the proposed AnoCLIP, we further introduce a test-time adaptation (TTA) mechanism to refine visual anomaly localization results, where we optimize a lightweight adapter in the visual encoder using AnoCLIP's pseudo-labels and noise-corrupted tokens. With both AnoCLIP and TTA, we significantly exploit the potential of CLIP for zero-shot anomaly localization and demonstrate the effectiveness of AnoCLIP on various datasets.

Yinsheng He, Xingyu Li

Recently, various deep learning methods have shown significant successes in medical image analysis, especially in the detection of cancer metastases in hematoxylin and eosin (H&E) stained whole-slide images (WSIs). However, in order to obtain good performance, these research achievements rely on hundreds of well-annotated WSIs. In this study, we tackle the tumor localization and detection problem under the setting of few labeled whole slide images and introduce a patch-based analysis pipeline based on the latest reverse knowledge distillation architecture. To address the extremely unbalanced normal and tumorous samples in training sample collection, we applied the focal loss formula to the representation similarity metric for model optimization. Compared with prior arts, our method achieves similar performance by less than ten percent of training samples on the public Camelyon16 dataset. In addition, this is the first work that show the great potential of the knowledge distillation models in computational histopathology.

Tianhang Nan, Hao Quan, Yong Ding et al.

Multiple Instance Learning (MIL) has garnered widespread attention in the field of Whole Slide Image (WSI) classification as it replaces pixel-level manual annotation with diagnostic reports as labels, significantly reducing labor costs. Recent research has shown that bag-level MIL methods often yield better results because they can consider all patches of the WSI as a whole. However, a drawback of such methods is the incorporation of more redundant patches, leading to interference. To extract patches with high diagnostic value while excluding interfering patches to address this issue, we developed an attention-based feature distillation multi-instance learning (AFD-MIL) approach. This approach proposed the exclusion of redundant patches as a preprocessing operation in weakly supervised learning, directly mitigating interference from extensive noise. It also pioneers the use of attention mechanisms to distill features with high diagnostic value, as opposed to the traditional practice of indiscriminately and forcibly integrating all patches. Additionally, we introduced global loss optimization to finely control the feature distillation module. AFD-MIL is orthogonal to many existing MIL methods, leading to consistent performance improvements. This approach has surpassed the current state-of-the-art method, achieving 91.47% ACC (accuracy) and 94.29% AUC (area under the curve) on the Camelyon16 (Camelyon Challenge 2016, breast cancer), while 93.33% ACC and 98.17% AUC on the TCGA-NSCLC (The Cancer Genome Atlas Program: non-small cell lung cancer). Different feature distillation methods were used for the two datasets, tailored to the specific diseases, thereby improving performance and interpretability.

Jian Zhu, Yu Cui, Zhangmin Huang et al.

The multi-view hash method converts heterogeneous data from multiple views into binary hash codes, which is one of the critical technologies in multimedia retrieval. However, the current methods mainly explore the complementarity among multiple views while lacking confidence learning and fusion. Moreover, in practical application scenarios, the single-view data contain redundant noise. To conduct the confidence learning and eliminate unnecessary noise, we propose a novel Adaptive Confidence Multi-View Hashing (ACMVH) method. First, a confidence network is developed to extract useful information from various single-view features and remove noise information. Furthermore, an adaptive confidence multi-view network is employed to measure the confidence of each view and then fuse multi-view features through a weighted summation. Lastly, a dilation network is designed to further enhance the feature representation of the fused features. To the best of our knowledge, we pioneer the application of confidence learning into the field of multimedia retrieval. Extensive experiments on two public datasets show that the proposed ACMVH performs better than state-of-the-art methods (maximum increase of 3.24%). The source code is available at https://github.com/HackerHyper/ACMVH.

Yifei Lin, Hanqiu Deng, Xingyu Li

Nowadays large computers extensively output logs to record the runtime status and it has become crucial to identify any suspicious or malicious activities from the information provided by the realtime logs. Thus, fast log anomaly detection is a necessary task to be implemented for automating the infeasible manual detection. Most of the existing unsupervised methods are trained only on normal log data, but they usually require either additional abnormal data for hyperparameter selection or auxiliary datasets for discriminative model optimization. In this paper, aiming for a highly effective discriminative model that enables rapid anomaly detection,we propose FastLogAD, a generator-discriminator framework trained to exhibit the capability of generating pseudo-abnormal logs through the Mask-Guided Anomaly Generation (MGAG) model and efficiently identifying the anomalous logs via the Discriminative Abnormality Separation (DAS) model. Particularly, pseudo-abnormal logs are generated by replacing randomly masked tokens in a normal sequence with unlikely candidates. During the discriminative stage, FastLogAD learns a distinct separation between normal and pseudoabnormal samples based on their embedding norms, allowing the selection of a threshold without exposure to any test data and achieving competitive performance. Extensive experiments on several common benchmarks show that our proposed FastLogAD outperforms existing anomaly detection approaches. Furthermore, compared to previous methods, FastLogAD achieves at least x10 speed increase in anomaly detection over prior work. Our implementation is available at https://github.com/YifeiLin0226/FastLogAD.

Qi Liu, Yanchen Liu, Ruifeng Li et al.

The integration of intelligent and connected technologies in modern vehicles, while offering enhanced functionalities through Electronic Control Unit (ECU) and interfaces like OBD-II and telematics, also exposes the vehicle's in-vehicle network (IVN) to potential cyberattacks. Unlike prior work, we identify a new time-exciting threat model against IVN. These attacks inject malicious messages that exhibit a time-exciting effect, gradually manipulating network traffic to disrupt vehicle operations and compromise safety-critical functions. We systematically analyze the characteristics of the threat: dynamism, time-exciting impact, and low prior knowledge dependency. To validate its practicality, we replicate the attack on a real Advanced Driver Assistance System via Controller Area Network (CAN), exploiting Unified Diagnostic Service vulnerabilities and proposing four attack strategies. While CAN's integrity checks mitigate attacks, Ethernet migration (e.g., DoIP/SOME/IP) introduces new surfaces. We further investigate the feasibility of time-exciting threat under SOME/IP. To detect time-exciting threat, we introduce MDHP-Net, leveraging Multi-Dimentional Hawkes Process (MDHP) and temporal and message-wise feature extracting structures. Meanwhile, to estimate MDHP parameters, we developed the first GPU-optimized gradient descent solver for MDHP (MDHP-GDS). These modules significantly improves the detection rate under time-exciting attacks in multi-ECU IVN system. To address data scarcity, we release STEIA9, the first open-source dataset for time-exciting attacks, covering 9 Ethernet-based attack scenarios. Extensive experiments on STEIA9 (9 attack scenarios) show MDHP-Net outperforms 3 baselines, confirming attack feasibility and detection efficacy.

Hanwen Liang, Konstantinos N. Plataniotis, Xingyu Li

Computational histopathology image diagnosis becomes increasingly popular and important, where images are segmented or classified for disease diagnosis by computers. While pathologists do not struggle with color variations in slides, computational solutions usually suffer from this critical issue. To address the issue of color variations in histopathology images, this study proposes two stain style transfer models, SSIM-GAN and DSCSI-GAN, based on the generative adversarial networks. By cooperating structural preservation metrics and feedback of an auxiliary diagnosis net in learning, medical-relevant information presented by image texture, structure, and chroma-contrast features is preserved in color-normalized images. Particularly, the smart treat of chromatic image content in our DSCSI-GAN model helps to achieve noticeable normalization improvement in image regions where stains mix due to histological substances co-localization. Extensive experimentation on public histopathology image sets indicates that our methods outperform prior arts in terms of generating more stain-consistent images, better preserving histological information in images, and obtaining significantly higher learning efficiency. Our python implementation is published on https://github.com/hanwen0529/DSCSI-GAN.

Yixin Hu, Xingyu Li

Wearing a mask is a strong protection against the COVID-19 pandemic, even though the vaccine has been successfully developed and is widely available. However, many people wear them incorrectly. This observation prompts us to devise an automated approach to monitor the condition of people wearing masks. Unlike previous studies, our work goes beyond mask detection; it focuses on generating a personalized demonstration on proper mask-wearing, which helps people use masks better through visual demonstration rather than text explanation. The pipeline starts from the detection of face covering. For images where faces are improperly covered, our mask overlay module incorporates statistical shape analysis (SSA) and dense landmark alignment to approximate the geometry of a face and generates corresponding face-covering examples. Our results show that the proposed system successfully identifies images with faces covered properly. Our ablation study on mask overlay suggests that the SSA model helps to address variations in face shapes, orientations, and scales. The final face-covering examples, especially half profile face images, surpass previous arts by a noticeable margin.

Ji Yang, Xinxin Zuo, Sen Wang et al.

Given a single image of a general object such as a chair, could we also restore its articulated 3D shape similar to human modeling, so as to animate its plausible articulations and diverse motions? This is an interesting new question that may have numerous downstream augmented reality and virtual reality applications. Comparing with previous efforts on object manipulation, our work goes beyond 2D manipulation and rigid deformation, and involves articulated manipulation. To achieve this goal, we propose an automated approach to build such 3D generic objects from single images and embed articulated skeletons in them. Specifically, our framework starts by reconstructing the 3D object from an input image. Afterwards, to extract skeletons for generic 3D objects, we develop a novel skeleton prediction method with a multi-head structure for skeleton probability field estimation by utilizing the deep implicit functions. A dataset of generic 3D objects with ground-truth annotated skeletons is collected. Empirically our approach is demonstrated with satisfactory performance on public datasets as well as our in-house dataset; our results surpass those of the state-of-the-arts by a noticeable margin on both 3D reconstruction and skeleton prediction.

Xingyu Li

Multiple stains are usually used to highlight biological substances in biomedical image analysis. To decompose multiple stains for co-localization quantification, blind source separation is usually performed. Prior model-based stain separation methods usually rely on stains' spatial distributions over an image and may fail to solve the co-localization problem. With the advantage of machine learning, deep generative models are used for this purpose. Since prior knowledge of imaging models is ignored in purely data-driven solutions, these methods may be sub-optimal. In this study, a novel learning-based blind source separation framework is proposed, where the physical model of biomedical imaging is incorporated to regularize the learning process. The introduced model-relevant adversarial loss couples all generators in the framework and limits the capacities of the generative models. Further more, a training algorithm is innovated for the proposed framework to avoid inter-generator confusion during learning. This paper particularly takes fluorescence unmixing in fluorescence microscopy images as an application example of the proposed framework. Qualitative and quantitative experimentation on a public fluorescence microscopy image set demonstrates the superiority of the proposed method over both prior model-based approaches and learning-based methods.

Xingyu Li, Konstantinos N. Plataniotis

Deep learning has achieved a great success in natural image classification. To overcome data-scarcity in computational pathology, recent studies exploit transfer learning to reuse knowledge gained from natural images in pathology image analysis, aiming to build effective pathology image diagnosis models. Since transferability of knowledge heavily depends on the similarity of the original and target tasks, significant differences in image content and statistics between pathology images and natural images raise the questions: how much knowledge is transferable? Is the transferred information equally contributed by pre-trained layers? To answer these questions, this paper proposes a framework to quantify knowledge gain by a particular layer, conducts an empirical investigation in pathology image centered transfer learning, and reports some interesting observations. Particularly, compared to the performance baseline obtained by random-weight model, though transferability of off-the-shelf representations from deep layers heavily depend on specific pathology image sets, the general representation generated by early layers does convey transferred knowledge in various image classification applications. The observation in this study encourages further investigation of specific metric and tools to quantify effectiveness and feasibility of transfer learning in future.

Xingyu Li, Marko Radulovic, Ksenija Kanjer et al.

Accurate diagnosis of breast cancer in histopathology images is challenging due to the heterogeneity of cancer cell growth as well as of a variety of benign breast tissue proliferative lesions. In this paper, we propose a practical and self-interpretable invasive cancer diagnosis solution. With minimum annotation information, the proposed method mines contrast patterns between normal and malignant images in unsupervised manner and generates a probability map of abnormalities to verify its reasoning. Particularly, a fully convolutional autoencoder is used to learn the dominant structural patterns among normal image patches. Patches that do not share the characteristics of this normal population are detected and analyzed by one-class support vector machine and 1-layer neural network. We apply the proposed method to a public breast cancer image set. Our results, in consultation with a senior pathologist, demonstrate that the proposed method outperforms existing methods. The obtained probability map could benefit the pathology practice by providing visualized verification data and potentially leads to a better understanding of data-driven diagnosis solutions.