Neyman-Pearson classification: parametrics and sample size requirement
This work addresses the problem of binary classification with prioritized error control for applications such as medical diagnosis, offering a parametric solution that is incremental over existing nonparametric methods.
The paper tackles the challenge of Neyman-Pearson classification, which prioritizes controlling type I error under a specified level while minimizing type II error, particularly in applications like rare disease diagnosis. It proposes a new parametric thresholding algorithm based on linear discriminant analysis that eliminates minimum sample size requirements for the scarce class, enabling use in small-sample scenarios, and introduces adaptive sample splitting to reduce type II error.
The Neyman-Pearson (NP) paradigm in binary classification seeks classifiers that achieve a minimal type II error while enforcing the prioritized type I error controlled under some user-specified level $α$. This paradigm serves naturally in applications such as severe disease diagnosis and spam detection, where people have clear priorities among the two error types. Recently, Tong, Feng and Li (2018) proposed a nonparametric umbrella algorithm that adapts all scoring-type classification methods (e.g., logistic regression, support vector machines, random forest) to respect the given type I error upper bound $α$ with high probability, without specific distributional assumptions on the features and the responses. Universal the umbrella algorithm is, it demands an explicit minimum sample size requirement on class $0$, which is often the more scarce class, such as in rare disease diagnosis applications. In this work, we employ the parametric linear discriminant analysis (LDA) model and propose a new parametric thresholding algorithm, which does not need the minimum sample size requirements on class $0$ observations and thus is suitable for small sample applications such as rare disease diagnosis. Leveraging both the existing nonparametric and the newly proposed parametric thresholding rules, we propose four LDA-based NP classifiers, for both low- and high-dimensional settings. On the theoretical front, we prove NP oracle inequalities for one proposed classifier, where the rate for excess type II error benefits from the explicit parametric model assumption. Furthermore, as NP classifiers involve a sample splitting step of class $0$ observations, we construct a new adaptive sample splitting scheme that can be applied universally to NP classifiers, and this adaptive strategy reduces the type II error of these classifiers.