A hybrid inverse problem in the fluorescence ultrasound modulated optical tomography in the diffusive regime
Provides theoretical guarantees and algorithms for a hybrid imaging modality, but is incremental as it extends known techniques to a specific problem setting.
The authors prove unique and stable reconstruction of fluorophore absorption and quantum efficiency coefficients from boundary measurements in fluorescence ultrasound modulated optical tomography, and propose numerically implemented reconstruction algorithms.
We investigate a hybrid inverse problem in fluorescence ultrasound modulated optical tomography (fUMOT) in the diffusive regime. We prove that the absorption coefficient of the fluorophores at the excitation frequency and the quantum efficiency coefficient can be uniquely and stably reconstructed from boundary measurement of the photon currents, provided that some background medium parameters are known. Reconstruction algorithms are proposed and numerically implemented as well.