Orthogonal Random Forest for Causal Inference
This addresses causal inference challenges in observational studies where controlling for many variables is needed, offering a provable solution with theoretical guarantees.
The paper tackles the problem of estimating heterogeneous treatment effects from observational data with high-dimensional confounding variables by proposing the orthogonal random forest algorithm, which achieves the same error rate as an oracle with prior knowledge of nuisance parameters under mild assumptions.
We propose the orthogonal random forest, an algorithm that combines Neyman-orthogonality to reduce sensitivity with respect to estimation error of nuisance parameters with generalized random forests (Athey et al., 2017)--a flexible non-parametric method for statistical estimation of conditional moment models using random forests. We provide a consistency rate and establish asymptotic normality for our estimator. We show that under mild assumptions on the consistency rate of the nuisance estimator, we can achieve the same error rate as an oracle with a priori knowledge of these nuisance parameters. We show that when the nuisance functions have a locally sparse parametrization, then a local $\ell_1$-penalized regression achieves the required rate. We apply our method to estimate heterogeneous treatment effects from observational data with discrete treatments or continuous treatments, and we show that, unlike prior work, our method provably allows to control for a high-dimensional set of variables under standard sparsity conditions. We also provide a comprehensive empirical evaluation of our algorithm on both synthetic and real data.