Retinal Image Segmentation with Small Datasets
This addresses the challenge of limited data for automated eye disease monitoring, which is incremental as it builds on existing deep learning methods but focuses on small datasets.
The paper tackled the problem of segmenting retinal layers and fluids in OCT images with very small datasets, achieving a mean Dice Score of 88% on the Duke DME dataset, outperforming human experts and state-of-the-art methods.
Many eye diseases like Diabetic Macular Edema (DME), Age-related Macular Degeneration (AMD), and Glaucoma manifest in the retina, can cause irreversible blindness or severely impair the central version. The Optical Coherence Tomography (OCT), a 3D scan of the retina with high qualitative information about the retinal morphology, can be used to diagnose and monitor changes in the retinal anatomy. Many Deep Learning (DL) methods have shared the success of developing an automated tool to monitor pathological changes in the retina. However, the success of these methods depend mainly on large datasets. To address the challenge from very small and limited datasets, we proposed a DL architecture termed CoNet (Coherent Network) for joint segmentation of layers and fluids in retinal OCT images on very small datasets (less than a hundred training samples). The proposed model was evaluated on the publicly available Duke DME dataset consisting of 110 B-Scans from 10 patients suffering from DME. Experimental results show that the proposed model outperformed both the human experts' annotation and the current state-of-the-art architectures by a clear margin with a mean Dice Score of 88% when trained on 55 images without any data augmentation.