On the Limits of Applying Graph Transformers for Brain Connectome Classification
This work addresses the challenge of evaluating graph-based methods for brain connectome analysis, highlighting dataset curation issues, but it is incremental as it primarily tests existing methods on new data.
The paper tackled the problem of applying graph transformers to brain connectome classification using the NeuroGraph benchmark, finding that they offer no major advantage over traditional GNNs and that models maintain accuracy even with all edges removed, suggesting graph structures may not impact predictions.
Brain connectomes offer detailed maps of neural connections within the brain. Recent studies have proposed novel connectome graph datasets and attempted to improve connectome classification by using graph deep learning. With recent advances demonstrating transformers' ability to model intricate relationships and outperform in various domains, this work explores their performance on the novel NeuroGraph benchmark datasets and synthetic variants derived from probabilistically removing edges to simulate noisy data. Our findings suggest that graph transformers offer no major advantage over traditional GNNs on this dataset. Furthermore, both traditional and transformer GNN models maintain accuracy even with all edges removed, suggesting that the dataset's graph structures may not significantly impact predictions. We propose further assessing NeuroGraph as a brain connectome benchmark, emphasizing the need for well-curated datasets and improved preprocessing strategies to obtain meaningful edge connections.