GNARFeb 4

Processing-in-memory for genomics workloads

arXiv:2506.005971 citationsh-index: 37
Originality Synthesis-oriented
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This work addresses the need for efficient genomic data analysis for life sciences and personalized medicine, but the abstract lacks concrete results or numbers, making it an early-stage proposal.

The BioPIM Project aims to leverage processing-in-memory (PIM) technologies to enable fast, energy-efficient, and cost-efficient analysis of genomics workloads, addressing the high energy and time costs of current data center-based approaches.

Low-cost, high-throughput DNA and RNA sequencing (HTS) data is the backbone of the life sciences. Genome sequencing is now becoming a part of Predictive, Preventive, Personalized, and Participatory (termed 'P4') medicine. All genomic data are currently processed in energy-hungry computer clusters and centers, necessitating data transfer, consuming substantial energy, and wasting valuable time. Therefore, there is a need for fast, energy-efficient, and cost-efficient technologies that enable genomics research without requiring data centers and cloud platforms. We recently launched the BioPIM Project to leverage emerging processing-in-memory (PIM) technologies to enable energy- and cost-efficient analysis of bioinformatics workloads. The BioPIM Project focuses on co-designing algorithms and data structures commonly used in genomics with several PIM architectures to achieve the highest cost, energy, and time savings.

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