IVAICVJun 16, 2025

Simple is what you need for efficient and accurate medical image segmentation

arXiv:2506.13415v12 citationsh-index: 9Has CodeExpert syst appl
Originality Highly original
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This work addresses the need for practical, efficient segmentation models in medical imaging, offering significant improvements over existing methods while maintaining high accuracy.

The paper tackles the problem of designing efficient and accurate medical image segmentation models by introducing SimpleUNet, an ultra-lightweight model with innovations like partial feature selection and adaptive feature fusion. It achieves record-breaking parameter efficiency (16 KB) and outperforms state-of-the-art models on multiple datasets, with results such as 85.76% mean DSC on breast lesion datasets.

While modern segmentation models often prioritize performance over practicality, we advocate a design philosophy prioritizing simplicity and efficiency, and attempted high performance segmentation model design. This paper presents SimpleUNet, a scalable ultra-lightweight medical image segmentation model with three key innovations: (1) A partial feature selection mechanism in skip connections for redundancy reduction while enhancing segmentation performance; (2) A fixed-width architecture that prevents exponential parameter growth across network stages; (3) An adaptive feature fusion module achieving enhanced representation with minimal computational overhead. With a record-breaking 16 KB parameter configuration, SimpleUNet outperforms LBUNet and other lightweight benchmarks across multiple public datasets. The 0.67 MB variant achieves superior efficiency (8.60 GFLOPs) and accuracy, attaining a mean DSC/IoU of 85.76%/75.60% on multi-center breast lesion datasets, surpassing both U-Net and TransUNet. Evaluations on skin lesion datasets (ISIC 2017/2018: mDice 84.86%/88.77%) and endoscopic polyp segmentation (KVASIR-SEG: 86.46%/76.48% mDice/mIoU) confirm consistent dominance over state-of-the-art models. This work demonstrates that extreme model compression need not compromise performance, providing new insights for efficient and accurate medical image segmentation. Codes can be found at https://github.com/Frankyu5666666/SimpleUNet.

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