LGNEOct 10, 2025

FedL2T: Personalized Federated Learning with Two-Teacher Distillation for Seizure Prediction

arXiv:2510.08984v1h-index: 1
Originality Incremental advance
AI Analysis

This provides a personalized solution for seizure prediction in privacy-sensitive healthcare, addressing inter-patient variability, but it is incremental as it builds on existing FL methods with novel distillation techniques.

The paper tackled the challenge of achieving robust seizure prediction performance under heterogeneous client settings in federated learning by proposing FedL2T, a personalized framework using a two-teacher distillation strategy, which outperformed state-of-the-art FL methods on EEG datasets, especially under low-label conditions, and reduced communication rounds.

The training of deep learning models in seizure prediction requires large amounts of Electroencephalogram (EEG) data. However, acquiring sufficient labeled EEG data is difficult due to annotation costs and privacy constraints. Federated Learning (FL) enables privacy-preserving collaborative training by sharing model updates instead of raw data. However, due to the inherent inter-patient variability in real-world scenarios, existing FL-based seizure prediction methods struggle to achieve robust performance under heterogeneous client settings. To address this challenge, we propose FedL2T, a personalized federated learning framework that leverages a novel two-teacher knowledge distillation strategy to generate superior personalized models for each client. Specifically, each client simultaneously learns from a globally aggregated model and a dynamically assigned peer model, promoting more direct and enriched knowledge exchange. To ensure reliable knowledge transfer, FedL2T employs an adaptive multi-level distillation strategy that aligns both prediction outputs and intermediate feature representations based on task confidence. In addition, a proximal regularization term is introduced to constrain personalized model updates, thereby enhancing training stability. Extensive experiments on two EEG datasets demonstrate that FedL2T consistently outperforms state-of-the-art FL methods, particularly under low-label conditions. Moreover, FedL2T exhibits rapid and stable convergence toward optimal performance, thereby reducing the number of communication rounds and associated overhead. These results underscore the potential of FedL2T as a reliable and personalized solution for seizure prediction in privacy-sensitive healthcare scenarios.

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