ZACH-ViT: A Zero-Token Vision Transformer with ShuffleStrides Data Augmentation for Robust Lung Ultrasound Classification
This addresses automated classification in medical imaging for critically ill patients, offering a robust solution with potential for real-time clinical use, though it is incremental in adapting Vision Transformers to specific data structures.
The paper tackled the challenge of classifying lung ultrasound videos to differentiate cardiogenic pulmonary oedema from non-cardiogenic and normal lungs, achieving the highest ROC-AUC of 0.80 on validation and 0.79 on test sets with a model that trains 1.35x faster than baselines.
Differentiating cardiogenic pulmonary oedema (CPE) from non-cardiogenic and structurally normal lungs in lung ultrasound (LUS) videos remains challenging due to the high visual variability of non-cardiogenic inflammatory patterns (NCIP/ARDS-like), interstitial lung disease, and healthy lungs. This heterogeneity complicates automated classification as overlapping B-lines and pleural artefacts are common. We introduce ZACH-ViT (Zero-token Adaptive Compact Hierarchical Vision Transformer), a 0.25 M-parameter Vision Transformer variant that removes both positional embeddings and the [CLS] token, making it fully permutation-invariant and suitable for unordered medical image data. To enhance generalization, we propose ShuffleStrides Data Augmentation (SSDA), which permutes probe-view sequences and frame orders while preserving anatomical validity. ZACH-ViT was evaluated on 380 LUS videos from 95 critically ill patients against nine state-of-the-art baselines. Despite the heterogeneity of the non-cardiogenic group, ZACH-ViT achieved the highest validation and test ROC-AUC (0.80 and 0.79) with balanced sensitivity (0.60) and specificity (0.91), while all competing models collapsed to trivial classification. It trains 1.35x faster than Minimal ViT (0.62M parameters) with 2.5x fewer parameters, supporting real-time clinical deployment. These results show that aligning architectural design with data structure can outperform scale in small-data medical imaging.