Yi R. Fung

Yujia Qin, Shengding Hu, Yankai Lin et al. · tsinghua

Humans possess an extraordinary ability to create and utilize tools, allowing them to overcome physical limitations and explore new frontiers. With the advent of foundation models, AI systems have the potential to be equally adept in tool use as humans. This paradigm, i.e., tool learning with foundation models, combines the strengths of specialized tools and foundation models to achieve enhanced accuracy, efficiency, and automation in problem-solving. Despite its immense potential, there is still a lack of a comprehensive understanding of key challenges, opportunities, and future endeavors in this field. To this end, we present a systematic investigation of tool learning in this paper. We first introduce the background of tool learning, including its cognitive origins, the paradigm shift of foundation models, and the complementary roles of tools and models. Then we recapitulate existing tool learning research into tool-augmented and tool-oriented learning. We formulate a general tool learning framework: starting from understanding the user instruction, models should learn to decompose a complex task into several subtasks, dynamically adjust their plan through reasoning, and effectively conquer each sub-task by selecting appropriate tools. We also discuss how to train models for improved tool-use capabilities and facilitate the generalization in tool learning. Considering the lack of a systematic tool learning evaluation in prior works, we experiment with 18 representative tools and show the potential of current foundation models in skillfully utilizing tools. Finally, we discuss several open problems that require further investigation for tool learning. In general, we hope this paper could inspire future research in integrating tools with foundation models.

Lifan Yuan, Yangyi Chen, Xingyao Wang et al.

Large language models (LLMs) are often augmented with tools to solve complex tasks. By generating code snippets and executing them through task-specific Application Programming Interfaces (APIs), they can offload certain functions to dedicated external modules, such as image encoding and performing calculations. However, most existing approaches to augment LLMs with tools are constrained by general-purpose APIs and lack the flexibility for tailoring them to specific tasks. In this work, we present CRAFT, a general tool creation and retrieval framework for LLMs. It creates toolsets specifically curated for the tasks and equips LLMs with a component that retrieves tools from these sets to enhance their capability to solve complex tasks. For each task, we collect specific code solutions by prompting GPT-4 to solve the training examples. Following a validation step ensuring the correctness, these solutions are abstracted into code snippets to enhance reusability, and deduplicated for higher quality. At inference time, the language model retrieves snippets from the toolsets and then executes them or generates the output conditioning on the retrieved snippets. Our method is designed to be flexible and offers a plug-and-play approach to adapt off-the-shelf LLMs to unseen domains and modalities, without any finetuning. Experiments on vision-language, tabular processing, and mathematical reasoning tasks show that our approach achieves substantial improvements compared to strong baselines. In addition, our in-depth analysis reveals that: (1) consistent performance improvement can be achieved by scaling up the number of tools and the capability of the backbone models; (2) each component of our approach contributes to the performance gains; (3) the created tools are well-structured and reliable with low complexity and atomicity. The code is available at https://github.com/lifan-yuan/CRAFT.

Yi R. Fung, Heng Ji

Online social networks such as Twitter and Weibo play an important role in how people stay informed and exchange reactions. Each crisis encompasses a new opportunity to study the portability of models for various tasks (e.g., information extraction, complex event understanding, misinformation detection, etc.), due to differences in domain, entities, and event types. We present the Russia-Ukraine Crisis Weibo (RUW) dataset, with over 3.5M user posts and comments in the first release. Our data is available at https://github.com/yrf1/RussiaUkraine_weibo_dataset.

Hanning Zhang, Shizhe Diao, Yong Lin et al.

Large language models (LLMs) have revolutionized numerous domains with their impressive performance but still face their challenges. A predominant issue is the propensity for these models to generate non-existent facts, a concern termed hallucination. Our research is motivated by the observation that previous instruction tuning methods force the model to complete a sentence no matter whether the model knows the knowledge or not. When the question is out of the parametric knowledge, it will try to make up something and fail to indicate when it lacks knowledge. In this paper, we present a new approach called Refusal-Aware Instruction Tuning (R-Tuning). This approach is formalized by first identifying the disparity in knowledge encompassed by pre-trained parameters compared to that of instruction tuning data. Then, we construct the refusal-aware data based on the knowledge intersection, to tune LLMs to refrain from responding to questions beyond its parametric knowledge. Experimental results demonstrate R-Tuning effectively improves a model's ability to answer known questions and refrain from answering unknown questions. Furthermore, when tested on out-of-domain datasets, the refusal ability was found to be a meta-skill that could be generalized to other tasks. Further analysis surprisingly finds that learning the uncertainty results in better calibration and an improved ability to estimate the uncertainty than uncertainty-based testing. Our code is available at https://github.com/shizhediao/R-Tuning.

Yi R. Fung, Tuhin Chakraborty, Hao Guo et al.

Norm discovery is important for understanding and reasoning about the acceptable behaviors and potential violations in human communication and interactions. We introduce NormSage, a framework for addressing the novel task of conversation-grounded multi-lingual, multi-cultural norm discovery, based on language model prompting and self-verification. NormSAGE leverages the expressiveness and implicit knowledge of the pretrained GPT-3 language model backbone, to elicit knowledge about norms through directed questions representing the norm discovery task and conversation context. It further addresses the risk of language model hallucination with a self-verification mechanism ensuring that the norms discovered are correct and are substantially grounded to their source conversations. Evaluation results show that our approach discovers significantly more relevant and insightful norms for conversations on-the-fly compared to baselines (>10+% in Likert scale rating). The norms discovered from Chinese conversation are also comparable to the norms discovered from English conversation in terms of insightfulness and correctness (<3% difference). In addition, the culture-specific norms are promising quality, allowing for 80% accuracy in culture pair human identification. Finally, our grounding process in norm discovery self-verification can be extended for instantiating the adherence and violation of any norm for a given conversation on-the-fly, with explainability and transparency. NormSAGE achieves an AUC of 95.4% in grounding, with natural language explanation matching human-written quality.

Ke Yang, Charles Yu, Yi Fung et al.

Several works have proven that finetuning is an applicable approach for debiasing contextualized word embeddings. Similarly, discrete prompts with semantic meanings have shown to be effective in debiasing tasks. With unfixed mathematical representation at the token level, continuous prompts usually surpass discrete ones at providing a pre-trained language model (PLM) with additional task-specific information. Despite this, relatively few efforts have been made to debias PLMs by prompt tuning with continuous prompts compared to its discrete counterpart. Furthermore, for most debiasing methods that alter a PLM's original parameters, a major problem is the need to not only decrease the bias in the PLM but also to ensure that the PLM does not lose its representation ability. Finetuning methods typically have a hard time maintaining this balance, as they tend to violently remove meanings of attribute words. In this paper, we propose ADEPT, a method to debias PLMs using prompt tuning while maintaining the delicate balance between removing biases and ensuring representation ability. To achieve this, we propose a new training criterion inspired by manifold learning and equip it with an explicit debiasing term to optimize prompt tuning. In addition, we conduct several experiments with regard to the reliability, quality, and quantity of a previously proposed attribute training corpus in order to obtain a clearer prototype of a certain attribute, which indicates the attribute's position and relative distances to other words on the manifold. We evaluate ADEPT on several widely acknowledged debiasing benchmarks and downstream tasks, and find that it achieves competitive results while maintaining (and in some cases even improving) the PLM's representation ability. We further visualize words' correlation before and after debiasing a PLM, and give some possible explanations for the visible effects.

Yuji Zhang, Sha Li, Jiateng Liu et al.

Hallucination is often regarded as a major impediment for using large language models (LLMs), especially for knowledge-intensive tasks. Even when the training corpus consists solely of true statements, language models still generate hallucinations in the form of amalgamations of multiple facts. We coin this phenomenon as ``knowledge overshadowing'': when we query knowledge from a language model with multiple conditions, some conditions overshadow others, leading to hallucinated outputs. This phenomenon partially stems from training data imbalance, which we verify on both pretrained models and fine-tuned models, over a wide range of LM model families and sizes.From a theoretical point of view, knowledge overshadowing can be interpreted as over-generalization of the dominant conditions (patterns). We show that the hallucination rate grows with both the imbalance ratio (between the popular and unpopular condition) and the length of dominant condition description, consistent with our derived generalization bound. Finally, we propose to utilize overshadowing conditions as a signal to catch hallucination before it is produced, along with a training-free self-contrastive decoding method to alleviate hallucination during inference. Our proposed approach showcases up to 82% F1 for hallucination anticipation and 11.2% to 39.4% hallucination control, with different models and datasets.

Chenkai Sun, Jinning Li, Yi R. Fung et al.

Automatic response forecasting for news media plays a crucial role in enabling content producers to efficiently predict the impact of news releases and prevent unexpected negative outcomes such as social conflict and moral injury. To effectively forecast responses, it is essential to develop measures that leverage the social dynamics and contextual information surrounding individuals, especially in cases where explicit profiles or historical actions of the users are limited (referred to as lurkers). As shown in a previous study, 97% of all tweets are produced by only the most active 25% of users. However, existing approaches have limited exploration of how to best process and utilize these important features. To address this gap, we propose a novel framework, named SocialSense, that leverages a large language model to induce a belief-centered graph on top of an existent social network, along with graph-based propagation to capture social dynamics. We hypothesize that the induced graph that bridges the gap between distant users who share similar beliefs allows the model to effectively capture the response patterns. Our method surpasses existing state-of-the-art in experimental evaluations for both zero-shot and supervised settings, demonstrating its effectiveness in response forecasting. Moreover, the analysis reveals the framework's capability to effectively handle unseen user and lurker scenarios, further highlighting its robustness and practical applicability.

Sandeep Polisetty, Juelin Liu, Kobi Falus et al.

Graph neural networks (GNNs), an emerging class of machine learning models for graphs, have gained popularity for their superior performance in various graph analytical tasks. Mini-batch training is commonly used to train GNNs on large graphs, and data parallelism is the standard approach to scale mini-batch training across multiple GPUs. Data parallel approaches contain redundant work as subgraphs sampled by different GPUs contain significant overlap. To address this issue, we introduce a hybrid parallel mini-batch training paradigm called split parallelism. Split parallelism avoids redundant work by splitting the sampling, loading, and training of each mini-batch across multiple GPUs. Split parallelism, however, introduces communication overheads that can be more than the savings from removing redundant work. We further present a lightweight partitioning algorithm that probabilistically minimizes these overheads. We implement split parallelism in GSplit and show that it outperforms state-of-the-art mini-batch training systems like DGL, Quiver, and $P^3$.

Revanth Gangi Reddy, Daniel Lee, Yi R. Fung et al.

Timely and comprehensive understanding of emerging events is crucial for effective decision-making; automating situation report generation can significantly reduce the time, effort, and cost for intelligence analysts. In this work, we identify intelligence analysts' practices and preferences for AI assistance in situation report generation to guide the design strategies for an effective, trust-building interface that aligns with their thought processes and needs. Next, we introduce SmartBook, an automated framework designed to generate situation reports from large volumes of news data, creating structured reports by automatically discovering event-related strategic questions. These reports include multiple hypotheses (claims), summarized and grounded to sources with factual evidence, to promote in-depth situation understanding. Our comprehensive evaluation of SmartBook, encompassing a user study alongside a content review with an editing study, reveals SmartBook's effectiveness in generating accurate and relevant situation reports. Qualitative evaluations indicate over 80% of questions probe for strategic information, and over 90% of summaries produce tactically useful content, being consistently favored over summaries from a large language model integrated with web search. The editing study reveals that minimal information is removed from the generated text (under 2.5%), suggesting that SmartBook provides analysts with a valuable foundation for situation reports

Sha Li, Chi Han, Pengfei Yu et al.

The recent explosion of performance of large language models (LLMs) has changed the field of Natural Language Processing (NLP) more abruptly and seismically than any other shift in the field's 80-year history. This has resulted in concerns that the field will become homogenized and resource-intensive. The new status quo has put many academic researchers, especially PhD students, at a disadvantage. This paper aims to define a new NLP playground by proposing 20+ PhD-dissertation-worthy research directions, covering theoretical analysis, new and challenging problems, learning paradigms, and interdisciplinary applications.

Haolin Yang, Jipeng Zhang, Zhitao He et al.

Translating natural language to SQL remains difficult for complex queries. Such queries often need environmental interaction and self-correction. To address this, we introduce MARS-SQL, a novel multi-agent framework that combines principled task decomposition and interactive reinforcement learning (RL). Our system comprises three specialized agents: a Grounding Agent for schema linking, a Generation Agent for query generation, and a Validation Agent for final selection. The core of our framework is the Generation agent, which is trained via a multi-turn RL policy. Adopting a ReAct-style Think-Act-Observe loop, the agent iteratively generates thoughts, executes SQL actions against a live database, and revises its strategy based on execution feedback, enabling dynamic, stateful reasoning and self-correction. At inference time, we generate multiple interaction trajectories to explore diverse reasoning paths. The Validation agent, then selects the optimal trajectory by modeling verification as a next-token prediction task and choosing the solution with the highest generation probability. This structured workflow pipelines specialized agents. It combines interactive RL for generation with generative modeling for verification. The approach proves highly effective for robust and accurate SQL generation. Experiments show that MARS-SQL achieves state-of-the-art Execution Accuracy of 77.84% on the BIRD dev set and 89.75% on the Spider test set. Our code is available at https://github.com/YangHaolin0526/MARS-SQL.

Kung-Hsiang Huang, Hou Pong Chan, Yi R. Fung et al.

Data visualization in the form of charts plays a pivotal role in data analysis, offering critical insights and aiding in informed decision-making. Automatic chart understanding has witnessed significant advancements with the rise of large foundation models in recent years. Foundation models, such as large language models, have revolutionized various natural language processing tasks and are increasingly being applied to chart understanding tasks. This survey paper provides a comprehensive overview of the recent developments, challenges, and future directions in chart understanding within the context of these foundation models. We review fundamental building blocks crucial for studying chart understanding tasks. Additionally, we explore various tasks and their evaluation metrics and sources of both charts and textual inputs. Various modeling strategies are then examined, encompassing both classification-based and generation-based approaches, along with tool augmentation techniques that enhance chart understanding performance. Furthermore, we discuss the state-of-the-art performance of each task and discuss how we can improve the performance. Challenges and future directions are addressed, highlighting the importance of several topics, such as domain-specific charts, lack of efforts in developing evaluation metrics, and agent-oriented settings. This survey paper serves as a comprehensive resource for researchers and practitioners in the fields of natural language processing, computer vision, and data analysis, providing valuable insights and directions for future research in chart understanding leveraging large foundation models. The studies mentioned in this paper, along with emerging new research, will be continually updated at: https://github.com/khuangaf/Awesome-Chart-Understanding.

Kung-Hsiang Huang, Mingyang Zhou, Hou Pong Chan et al.

Recent advancements in large vision-language models (LVLMs) have led to significant progress in generating natural language descriptions for visual content and thus enhancing various applications. One issue with these powerful models is that they sometimes produce texts that are factually inconsistent with the visual input. While there has been some effort to mitigate such inconsistencies in natural image captioning, the factuality of generated captions for structured document images, such as charts, has not received as much scrutiny, posing a potential threat to information reliability in critical applications. This work delves into the factuality aspect by introducing a comprehensive typology of factual errors in generated chart captions. A large-scale human annotation effort provides insight into the error patterns and frequencies in captions crafted by various chart captioning models, ultimately forming the foundation of a novel dataset, CHOCOLATE. Our analysis reveals that even state-of-the-art models, including GPT-4V, frequently produce captions laced with factual inaccuracies. In response to this challenge, we establish the new task of Chart Caption Factual Error Correction and introduce CHARTVE, a model for visual entailment that outperforms proprietary and open-source LVLMs in evaluating factual consistency. Furthermore, we propose C2TFEC, an interpretable two-stage framework that excels at correcting factual errors. This work inaugurates a new domain in factual error correction for chart captions, presenting a novel evaluation mechanism, and demonstrating an effective approach to ensuring the factuality of generated chart captions. The code and data as well as the continuously updated benchmark can be found at: https://khuangaf.github.io/CHOCOLATE/.

Dadi Guo, Qingyu Liu, Dongrui Liu et al.

Large Language Model (LLM)-based agents are increasingly used as autonomous subordinates that carry out tasks for users. This raises the question of whether they may also engage in deception, similar to how individuals in human organizations lie to superiors to create a good image or avoid punishment. We observe and define agentic upward deception, a phenomenon in which an agent facing environmental constraints conceals its failure and performs actions that were not requested without reporting. To assess its prevalence, we construct a benchmark of 200 tasks covering five task types and eight realistic scenarios in a constrained environment, such as broken tools or mismatched information sources. Evaluations of 11 popular LLMs reveal that these agents typically exhibit action-based deceptive behaviors, such as guessing results, performing unsupported simulations, substituting unavailable information sources, and fabricating local files. We further test prompt-based mitigation and find only limited reductions, suggesting that it is difficult to eliminate and highlighting the need for stronger mitigation strategies to ensure the safety of LLM-based agents.

Yuchen Huang, Zhiyuan Fan, Zhitao He et al.

Pretrained vision-language models (VLMs) such as CLIP excel in general multimodal comprehension but often struggle to capture nuanced, context-dependent visual cues. This makes it difficult to distinguish between similar-looking concepts with potentially different cultural meanings. Such deficiencies are mainly due to a limited amount of high-quality cultural data, contextual information, and the lack of negative examples that highlight subtle differences. To mitigate this, we design a data curation pipeline leveraging open-sourced VLMs and text-to-image models to construct CulTwin, a synthetic cultural dataset. This dataset consists of paired concept-caption-image triplets, where concepts visually resemble each other but are culturally different. Then, we fine-tune CLIP on CulTwin to develop CultureCLIP, which aligns cultural concepts with contextually enhanced captions and synthetic images through tailored contrastive learning. Experiments on culture-specific benchmarks show that CultureCLIP outperforms the base CLIP, achieving up to a notable 5.49% improvement in fine-grained concept recognition on certain tasks while preserving CLIP's original generalization ability, validating the effectiveness of our data synthesis and VLM backbone training paradigm in capturing subtle cultural distinctions.

Yuchen Huang, Sijia Li, Minghao Liu et al.

LLM-based agents can autonomously accomplish complex tasks across various domains. However, to further cultivate capabilities such as adaptive behavior and long-term decision-making, training on static datasets built from human-level knowledge is insufficient. These datasets are costly to construct and lack both dynamism and realism. A growing consensus is that agents should instead interact directly with environments and learn from experience through reinforcement learning. We formalize this iterative process as the Generation-Execution-Feedback (GEF) loop, where environments generate tasks to challenge agents, return observations in response to agents' actions during task execution, and provide evaluative feedback on rollouts for subsequent learning. Under this paradigm, environments function as indispensable producers of experiential data, highlighting the need to scale them toward greater complexity, realism, and interactivity. In this survey, we systematically review representative methods for environment scaling from a pioneering environment-centric perspective and organize them along the stages of the GEF loop, namely task generation, task execution, and feedback. We further analyze benchmarks, implementation strategies, and applications, consolidating fragmented advances and outlining future research directions for agent intelligence.

Ke Yang, Jiateng Liu, John Wu et al.

The prominent large language models (LLMs) of today differ from past language models not only in size, but also in the fact that they are trained on a combination of natural language and formal language (code). As a medium between humans and computers, code translates high-level goals into executable steps, featuring standard syntax, logical consistency, abstraction, and modularity. In this survey, we present an overview of the various benefits of integrating code into LLMs' training data. Specifically, beyond enhancing LLMs in code generation, we observe that these unique properties of code help (i) unlock the reasoning ability of LLMs, enabling their applications to a range of more complex natural language tasks; (ii) steer LLMs to produce structured and precise intermediate steps, which can then be connected to external execution ends through function calls; and (iii) take advantage of code compilation and execution environment, which also provides diverse feedback for model improvement. In addition, we trace how these profound capabilities of LLMs, brought by code, have led to their emergence as intelligent agents (IAs) in situations where the ability to understand instructions, decompose goals, plan and execute actions, and refine from feedback are crucial to their success on downstream tasks. Finally, we present several key challenges and future directions of empowering LLMs with code.

Chi Han, Jialiang Xu, Manling Li et al.

Language models (LMs) automatically learn word embeddings during pre-training on language corpora. Although word embeddings are usually interpreted as feature vectors for individual words, their roles in language model generation remain underexplored. In this work, we theoretically and empirically revisit output word embeddings and find that their linear transformations are equivalent to steering language model generation styles. We name such steers LM-Steers and find them existing in LMs of all sizes. It requires learning parameters equal to 0.2% of the original LMs' size for steering each style. On tasks such as language model detoxification and sentiment control, LM-Steers can achieve comparable or superior performance compared with state-of-the-art controlled generation methods while maintaining a better balance with generation quality. The learned LM-Steer serves as a lens in text styles: it reveals that word embeddings are interpretable when associated with language model generations and can highlight text spans that most indicate the style differences. An LM-Steer is transferrable between different language models by an explicit form calculation. One can also continuously steer LMs simply by scaling the LM-Steer or compose multiple LM-Steers by adding their transformations. Our codes are publicly available at \url{https://github.com/Glaciohound/LM-Steer}.

Chenkai Sun, Ke Yang, Revanth Gangi Reddy et al.

The increasing demand for personalized interactions with large language models (LLMs) calls for methodologies capable of accurately and efficiently identifying user opinions and preferences. Retrieval augmentation emerges as an effective strategy, as it can accommodate a vast number of users without the costs from fine-tuning. Existing research, however, has largely focused on enhancing the retrieval stage and devoted limited exploration toward optimizing the representation of the database, a crucial aspect for tasks such as personalization. In this work, we examine the problem from a novel angle, focusing on how data can be better represented for more data-efficient retrieval in the context of LLM customization. To tackle this challenge, we introduce Persona-DB, a simple yet effective framework consisting of a hierarchical construction process to improve generalization across task contexts and collaborative refinement to effectively bridge knowledge gaps among users. In the evaluation of response prediction, Persona-DB demonstrates superior context efficiency in maintaining accuracy with a significantly reduced retrieval size, a critical advantage in scenarios with extensive histories or limited context windows. Our experiments also indicate a marked improvement of over 10% under cold-start scenarios, when users have extremely sparse data. Furthermore, our analysis reveals the increasing importance of collaborative knowledge as the retrieval capacity expands.

Keyang Xuan, Li Yi, Fan Yang et al.

The rise of multimodal misinformation on social platforms poses significant challenges for individuals and societies. Its increased credibility and broader impact compared to textual misinformation make detection complex, requiring robust reasoning across diverse media types and profound knowledge for accurate verification. The emergence of Large Vision Language Model (LVLM) offers a potential solution to this problem. Leveraging their proficiency in processing visual and textual information, LVLM demonstrates promising capabilities in recognizing complex information and exhibiting strong reasoning skills. In this paper, we first investigate the potential of LVLM on multimodal misinformation detection. We find that even though LVLM has a superior performance compared to LLMs, its profound reasoning may present limited power with a lack of evidence. Based on these observations, we propose LEMMA: LVLM-Enhanced Multimodal Misinformation Detection with External Knowledge Augmentation. LEMMA leverages LVLM intuition and reasoning capabilities while augmenting them with external knowledge to enhance the accuracy of misinformation detection. Our method improves the accuracy over the top baseline LVLM by 7% and 13% on Twitter and Fakeddit datasets respectively.

Shijue Huang, Hongru Wang, Wanjun Zhong et al. · pku

Modern large reasoning models demonstrate impressive problem-solving capabilities by employing sophisticated reasoning strategies. However, they often struggle to balance efficiency and effectiveness, frequently generating unnecessarily lengthy reasoning chains for simple problems. In this work, we propose AdaCtrl, a novel framework to support both difficulty-aware adaptive reasoning budget allocation and explicit user control over reasoning depth. AdaCtrl dynamically adjusts its reasoning length based on self-assessed problem difficulty, while also allowing users to manually control the budget to prioritize either efficiency or effectiveness. This is achieved through a two-stage training pipeline: an initial cold-start fine-tuning phase to instill the ability to self-aware difficulty and adjust reasoning budget, followed by a difficulty-aware reinforcement learning (RL) stage that refines the model's adaptive reasoning strategies and calibrates its difficulty assessments based on its evolving capabilities during online training. To enable intuitive user interaction, we design explicit length-triggered tags that function as a natural interface for budget control. Empirical results show that AdaCtrl adapts reasoning length based on estimated difficulty, compared to the standard training baseline that also incorporates fine-tuning and RL, it yields performance improvements and simultaneously reduces response length by 10.06% and 12.14% on the more challenging AIME2024 and AIME2025 datasets, which require elaborate reasoning, and by 62.05% and 91.04% on the MATH500 and GSM8K datasets, where more concise responses are sufficient. Furthermore, AdaCtrl enables precise user control over the reasoning budget, allowing for tailored responses to meet specific needs.

Yuji Zhang, Sha Li, Cheng Qian et al.

Hallucination is a persistent challenge in large language models (LLMs), where even with rigorous quality control, models often generate distorted facts. This paradox, in which error generation continues despite high-quality training data, calls for a deeper understanding of the underlying LLM mechanisms. To address it, we propose a novel concept: knowledge overshadowing, where model's dominant knowledge can obscure less prominent knowledge during text generation, causing the model to fabricate inaccurate details. Building on this idea, we introduce a novel framework to quantify factual hallucinations by modeling knowledge overshadowing. Central to our approach is the log-linear law, which predicts that the rate of factual hallucination increases linearly with the logarithmic scale of (1) Knowledge Popularity, (2) Knowledge Length, and (3) Model Size. The law provides a means to preemptively quantify hallucinations, offering foresight into their occurrence even before model training or inference. Built on overshadowing effect, we propose a new decoding strategy CoDa, to mitigate hallucinations, which notably enhance model factuality on Overshadow (27.9%), MemoTrap (13.1%) and NQ-Swap (18.3%). Our findings not only deepen understandings of the underlying mechanisms behind hallucinations but also provide actionable insights for developing more predictable and controllable language models.

Dadi Guo, Jiayu Liu, Zhiyuan Fan et al.

Large reasoning models (e.g., R1, o3) have demonstrated remarkable mathematical problem-solving abilities. However, the high reported accuracy of these advanced models on popular datasets, reliance on purely numerical evaluation and potential benchmark leakage, often masks their true reasoning shortcomings. To address this, we propose leveraging the inherent rigor and methodological complexity of mathematical proofs as a diagnostic tool to expose these hidden failures. Specifically, we introduce the RFMDataset (Reveal Failure Modes), a collection of 200 diverse mathematical proof problems, and thoroughly evaluate advanced models' performance on it. Our in-depth analysis of their failures uncovers 10 fine-grained error types, which shows fundamental limitations in current large reasoning models: 1) large reasoning models grapple profoundly with mathematical proofs, with some generating entirely correct proofs for less than 20% of problems and failing even on basic ones; 2) models exhibit a diverse spectrum of reasoning failures, prominently demonstrating the lack of guarantees for the correctness and rigor of single-step reasoning; and 3) models show hallucination and incompleteness during the reasoning process. Our findings reveal that models' self-reflection is insufficient to resolve the current logical dilemmas, necessitating formalized and fine-grained logical training.

Ruida Wang, Yuxin Li, Yi R. Fung et al.

Enhancing the mathematical reasoning capabilities of LLMs has garnered significant attention in both the mathematical and computer science communities. Recent works have made substantial progress in both Natural Language (NL) reasoning and Formal Language (FL) reasoning by leveraging the potential of pure Reinforcement Learning (RL) methods on base models. However, RL approaches struggle to impart new capabilities not presented in the base model, highlighting the need to integrate more knowledge like FL into NL math reasoning effectively. Yet, this integration is challenging due to inherent disparities in problem structure and reasoning format between NL and FL. To address these challenges, we introduce **NL-FL HybridReasoning (NFL-HR)**, an end-to-end framework designed to incorporate the FL expert into NL math problem-solving. To bridge the NL and FL input format gap, we propose the NL-FL Problem Alignment method, which reformulates the Question-Answering (QA) problems in NL as existence theorems in FL. Subsequently, the Mixed Problem Input technique we provide enables the FL reasoner to handle both QA and existence problems concurrently. Lastly, we mitigate the NL and FL output format gap in reasoning through an LLM-based Answer Extraction mechanism. Comprehensive experiments demonstrate that the NFL-HR framework achieves **89.80**% and **84.34%** accuracy rates on the MATH-500 and the AMC benchmarks, surpassing the NL baseline by **4.60%** and **4.82%**, respectively. Notably, some problems resolved by our framework remain unsolved by the NL baseline model even under a larger number of trials.

Zhitao He, Sandeep Polisetty, Zhiyuan Fan et al.

In recent years, multimodal large language models (MLLMs) have made significant progress but continue to face inherent challenges in multimodal reasoning, which requires multi-level (e.g., perception, reasoning) and multi-granular (e.g., multi-step reasoning chain) advanced inferencing. Prior work on estimating model confidence tends to focus on the overall response for training and calibration, but fails to assess confidence in each reasoning step, leading to undesirable hallucination snowballing. In this work, we present MMBoundary, a novel framework that advances the knowledge boundary awareness of MLLMs through reasoning step confidence calibration. To achieve this, we propose to incorporate complementary textual and cross-modal self-rewarding signals to estimate confidence at each step of the MLLM reasoning process. In addition to supervised fine-tuning MLLM on this set of self-rewarded confidence estimation signal for initial confidence expression warm-up, we introduce a reinforcement learning stage with multiple reward functions for further aligning model knowledge and calibrating confidence at each reasoning step, enhancing reasoning chain self-correction. Empirical results show that MMBoundary significantly outperforms existing methods across diverse domain datasets and metrics, achieving an average of 7.5% reduction in multimodal confidence calibration errors and up to 8.3% improvement in task performance.

Yumeng Wang, Zhiyuan Fan, Jiayu Liu et al.

Large Reasoning Models (LRMs) with long chain-of-thought capabilities, optimized via reinforcement learning with verifiable rewards (RLVR), excel at objective reasoning tasks like mathematical problem solving and code generation. However, RLVR is known for degrading generation diversity, which causes LRMs to fall short on subjective reasoning that has multiple answers depending on different role perspectives. While recent studies recognize the importance of diversity-enhanced training in objective reasoning, limited attention has been given to subjective tasks. In this paper, we find that subjective reasoning can be improved by introducing perspective diversity and token-level diversity, with the former one providing a coherent scaffolding anchored to a real-world stakeholder group and the latter one broadening the answer search space. We propose MultiRole-R1, a diversity-enhanced training framework featuring an unsupervised data construction pipeline that synthesizes reasoning chains incorporating various role perspectives. It also employs reinforcement learning via Group Relative Policy Optimization with reward shaping, taking diversity as a reward signal in addition to verifiable reward. Training on subjective tasks solely, MultiRole-R1 increases the in-domain and out-of-domain accuracy by 14.1% and 7.64%, and even enhances the performance on advanced math reasoning such as AIME 2024. We further show that diversity is a more consistent indicator of accuracy than reasoning length.

Hengzhi Li, Megan Tjandrasuwita, Yi R. Fung et al.

As AI becomes more closely integrated with peoples' daily activities, socially intelligent AI that can understand and interact seamlessly with humans in daily lives is increasingly important. However, current works in AI social reasoning all rely on language-only or language-dominant approaches to benchmark and training models, resulting in systems that are improving in verbal communication but struggle with nonverbal social understanding. To address this limitation, we tap into a novel data source rich in nonverbal social interactions -- mime videos. Mimes refer to the art of expression through gesture and movement without spoken words, which presents unique challenges and opportunities in interpreting nonverbal social communication. We contribute a new dataset called MimeQA, obtained by sourcing 8 hours of videos clips from YouTube and developing a comprehensive video question-answering benchmark comprising 806 carefully annotated and verified question-answer pairs, designed to probe nonverbal social reasoning capabilities. Using MimeQA, we evaluate state-of-the-art video large language models (vLLMs) and find that they achieve low overall accuracy, ranging from 20-30%, while humans score 86%. Our analysis reveals that vLLMs often fail to ground imagined objects and over-rely on the text prompt while ignoring subtle nonverbal interactions. We hope to inspire future work in AI models that embody true social intelligence capable of interpreting non-verbal human interactions.

Zhiyuan Fan, Yumeng Wang, Sandeep Polisetty et al.

Large Vision Language Models (LVLMs) excel in various vision-language tasks. Yet, their robustness to visual variations in position, scale, orientation, and context that objects in natural scenes inevitably exhibit due to changes in viewpoint and environment remains largely underexplored. To bridge this gap, we introduce V$^2$R-Bench, a comprehensive benchmark framework for evaluating Visual Variation Robustness of LVLMs, which encompasses automated evaluation dataset generation and principled metrics for thorough robustness assessment. Through extensive evaluation on 21 LVLMs, we reveal a surprising vulnerability to visual variations, in which even advanced models that excel at complex vision-language tasks significantly underperform on simple tasks such as object recognition. Interestingly, these models exhibit a distinct visual position bias that contradicts theories of effective receptive fields, and demonstrate a human-like visual acuity threshold. To identify the source of these vulnerabilities, we present a systematic framework for component-level analysis, featuring a novel visualization approach for aligned visual features. Results show that these vulnerabilities stem from error accumulation in the pipeline architecture and inadequate multimodal alignment. Complementary experiments with synthetic data further demonstrate that these limitations are fundamentally architectural deficiencies, scoring the need for architectural innovations in future LVLM designs.

Junsheng Huang, Zhitao He, Yucheng Huang et al.

The hallucination of non-existent facts by LLMs is an important problem given its widespread adoption across various applications. Previous research addresses this problem by analyzing the internal parameterized knowledge boundaries to estimate confidence. However, these studies focus on the single-problem setting and have not explored the more challenging multi-problem setting, which requires accurately answering multiple questions simultaneously. We introduce a novel method for the multi-problem setting, Multiple Answers and Confidence Stepwise Tuning (MAC-Tuning), that separates the learning of answer prediction and confidence estimation during fine-tuning on instruction data. Extensive experiments demonstrate that our method outperforms baselines by up to 25\% in average precision.

Minghao Liu, Zhitao He, Zhiyuan Fan et al.

Text-guided image editing has seen significant progress in natural image domains, but its application in medical imaging remains limited and lacks standardized evaluation frameworks. Such editing could revolutionize clinical practices by enabling personalized surgical planning, enhancing medical education, and improving patient communication. To bridge this gap, we introduce MedEBench1, a robust benchmark designed to diagnose reliability in text-guided medical image editing. MedEBench consists of 1,182 clinically curated image-prompt pairs covering 70 distinct editing tasks and 13 anatomical regions. It contributes in three key areas: (1) a clinically grounded evaluation framework that measures Editing Accuracy, Context Preservation, and Visual Quality, complemented by detailed descriptions of intended edits and corresponding Region-of-Interest (ROI) masks; (2) a comprehensive comparison of seven state-of-theart models, revealing consistent patterns of failure; and (3) a diagnostic error analysis technique that leverages attention alignment, using Intersection-over-Union (IoU) between model attention maps and ROI masks to identify mislocalization issues, where models erroneously focus on incorrect anatomical regions. MedEBench sets the stage for developing more reliable and clinically effective text-guided medical image editing tools.

Jaewoo Lee, Keyang Xuan, Chanakya Ekbote et al.

Multimodal Large Language Models (MLLMs) have shown remarkable versatility in understanding diverse multimodal data and tasks. However, these capabilities come with an increased model scale. While post-training pruning reduces model size in unimodal models, its application to MLLMs often yields limited success. Our analysis discovers that conventional methods fail to account for the unique token attributes across layers and modalities inherent to MLLMs. Inspired by this observation, we propose TAMP, a simple yet effective pruning framework tailored for MLLMs, featuring two key components: (1) Diversity-Aware Sparsity, which adjusts sparsity ratio per layer based on diversities among multimodal output tokens, preserving more parameters in high-diversity layers; and (2) Adaptive Multimodal Input Activation, which identifies representative multimodal input tokens using attention scores to guide unstructured weight pruning. We validate our method on two state-of-the-art MLLMs: LLaVA-NeXT, designed for vision-language tasks, and VideoLLaMA2, capable of processing audio, visual, and language modalities. Empirical experiments across various multimodal evaluation benchmarks demonstrate that each component of our approach substantially outperforms existing pruning techniques.

Zhitao He, Haolin Yang, Zeyu Qin et al.

The significant gap between rising demands for clinical training and the scarcity of expert instruction poses a major challenge to medical education. With powerful capabilities in personalized guidance, Large Language Models (LLMs) offer a promising solution to bridge this gap. However, current research focuses mainly on one-on-one knowledge instruction, overlooking collaborative reasoning, a key skill for students developed in teamwork like ward rounds. To this end, we develop ClinEdu, a multi-agent pedagogical simulator with personality-driven patients and diverse student cohorts, enabling controlled testing of complex pedagogical processes and scalable generation of teaching data. Based on ClinEdu, we construct ClinTeach, a large Socratic teaching dialogue dataset that captures the complexities of group instruction. We then train MedTutor-R1, the first multimodal Socratic tutor designed for one-to-many instruction in clinical medical education. MedTutor-R1 is first instruction-tuned on our ClinTeach dataset and then optimized with reinforcement learning, using rewards derived from a three-axis rubric, covering structural fidelity, analytical quality, and clinical safety, to refine its adaptive Socratic strategies. For authentic in-situ assessment, we use simulation-based interactive evaluation that redeploys the tutor back into ClinEdu. Experimental results demonstrate that our MedTutor-R1 outperforms the base model by over 20% in average pedagogical score and is comparable to o3, while also exhibiting high adaptability in handling a varying number of students. This promising performance underscores the effectiveness of our pedagogical simulator, ClinEdu.

Zheyu Fan, Jiateng Liu, Yuji Zhang et al.

Humans naturally perform temporal screening by dragging the progress bar and focusing on salient temporal segments, but current Video Large Language Models (Video-LLMs) struggle to capture fine-grained temporal semantics due to sparse frame sampling and insufficient inter-frame reasoning supervision during their training. To address this, Inspired by well-established cognitive science principles, we propose Temporal Visual Screening (TVS), a new task that universally pre-processes video question answering and instruction tuning data by: (1) retaining focus-critical video segments, (2) synchronously reconstructing queries to their most direct form while preserving answer consistency, and (3) keeping the invariance and consistency for any possible answer. TVS is formulated as a modular front-end adapter task that can be seamlessly integrated into both Video Instruction Tuning (training) and Video Question Answering (inference) pipelines. TVS optimizes distribution of reasoning burden and cognitive load; during training, it aligns queries with focus-critical visual information; at inference, it enables query-aware segment focus and streamlined query representations. In particular, we curate the first benchmark for TVS and propose ReSimplifyIt, a baseline outperforming prior approaches on seemingly similar tasks by 0.47 in F-1 score on video trimming while achieving competitive query rewriting performance. Experiments demonstrate that incorporating TVS yields relative gains of 7.33% (training) and 34.6% (inference), demonstrating the effectiveness of temporal information screening for improving video-language understanding.

Xinyi Liu, Dachun Sun, Yi R. Fung et al.

Despite the impressive capabilities of Large Language Models (LLMs), existing Conversational Health Agents (CHAs) remain static and brittle, incapable of adaptive multi-turn reasoning, symptom clarification, or transparent decision-making. This hinders their real-world applicability in clinical diagnosis, where iterative and structured dialogue is essential. We propose DocCHA, a confidence-aware, modular framework that emulates clinical reasoning by decomposing the diagnostic process into three stages: (1) symptom elicitation, (2) history acquisition, and (3) causal graph construction. Each module uses interpretable confidence scores to guide adaptive questioning, prioritize informative clarifications, and refine weak reasoning links. Evaluated on two real-world Chinese consultation datasets (IMCS21, DX), DocCHA consistently outperforms strong prompting-based LLM baselines (GPT-3.5, GPT-4o, LLaMA-3), achieving up to 5.18 percent higher diagnostic accuracy and over 30 percent improvement in symptom recall, with only modest increase in dialogue turns. These results demonstrate the effectiveness of DocCHA in enabling structured, transparent, and efficient diagnostic conversations -- paving the way for trustworthy LLM-powered clinical assistants in multilingual and resource-constrained settings.

Yu Huang, Junhao Chen, Shuliang Liu et al. · tsinghua

The rapid development of Artificial Intelligence Generated Content (AIGC) has led to significant progress in video generation, but also raises serious concerns about intellectual property protection and reliable content tracing. Watermarking is a widely adopted solution to this issue, yet existing methods for video generation mainly follow a post-generation paradigm, which often fails to effectively balance the trade-off between video quality and watermark extraction. Meanwhile, current in-generation methods that embed the watermark into the initial Gaussian noise usually incur substantial additional computation. To address these issues, we propose \textbf{Video Signature} (\textsc{VidSig}), an implicit watermarking method for video diffusion models that enables imperceptible and adaptive watermark integration during video generation with almost no extra latency. Specifically, we partially fine-tune the latent decoder, where \textbf{Perturbation-Aware Suppression} (PAS) pre-identifies and freezes perceptually sensitive layers to preserve visual quality. Beyond spatial fidelity, we further enhance temporal consistency by introducing a lightweight \textbf{Temporal Alignment} module that guides the decoder to generate coherent frame sequences during fine-tuning. Experimental results show that \textsc{VidSig} achieves the best trade-off among watermark extraction accuracy, video quality, and watermark latency. It also demonstrates strong robustness against both spatial and temporal tamper, and remains stable across different video lengths and resolutions, highlighting its practicality in real-world scenarios.

Yiming Huang, Junyan Zhang, Zihao Wang et al.

Large Language Models (LLMs) have become powerful, but hallucinations remain a vital obstacle to their trustworthy use. While previous works improved the capability of hallucination detection by measuring uncertainty, they all lack the ability to explain the provenance behind why hallucinations occur, i.e., which part of the inputs tends to trigger hallucinations. Recent works on the prompt attack indicate that uncertainty exists in semantic propagation, where attention mechanisms gradually fuse local token information into high-level semantics across layers. Meanwhile, uncertainty also emerges in language generation, due to its probability-based selection of high-level semantics for sampled generations. Based on that, we propose RePPL to recalibrate uncertainty measurement by these two aspects, which dispatches explainable uncertainty scores to each token and aggregates in Perplexity-style Log-Average form as total score. Experiments show that our method achieves the best comprehensive detection performance across various QA datasets on advanced models (average AUC of 0.833), and our method is capable of producing token-level uncertainty scores as explanations for the hallucination. Leveraging these scores, we preliminarily find the chaotic pattern of hallucination and showcase its promising usage.

Shujin Wu, Cheng Qian, Yi R. Fung et al.

The growing capabilities of large language models (LLMs) present a key challenge of maintaining effective human oversight. Weak-to-strong generalization (W2SG) offers a promising framework for supervising increasingly capable LLMs using weaker ones. Traditional W2SG methods rely on passive learning, where a weak teacher provides noisy demonstrations to train a strong student. This hinders students from employing their knowledge during training and reaching their full potential. In this work, we introduce Alice (pro{A}ctive {l}earning w{i}th tea{c}her's D{e}monstrations), a framework that leverages complementary knowledge between teacher and student to enhance the learning process. We probe the knowledge base of the teacher model by eliciting their uncertainty, and then use these insights together with teachers' responses as demonstrations to guide student models in self-generating improved responses for supervision. In addition, for situations with significant capability gaps between teacher and student models, we introduce cascade Alice, which employs a hierarchical training approach where weak teachers initially supervise intermediate models, who then guide stronger models in sequence. Experimental results demonstrate that our method significantly enhances the W2SG performance, yielding substantial improvements in three key tasks compared to the original W2SG: knowledge-based reasoning (+4.0%), mathematical reasoning (+22.62%), and logical reasoning (+12.11%). This highlights the effectiveness of our new W2SG paradigm that enables more robust knowledge transfer and supervision outcome.

Mingyang Zhou, Yi R. Fung, Long Chen et al.

Building cross-model intelligence that can understand charts and communicate the salient information hidden behind them is an appealing challenge in the vision and language(V+L) community. The capability to uncover the underlined table data of chart figures is a critical key to automatic chart understanding. We introduce ChartT5, a V+L model that learns how to interpret table information from chart images via cross-modal pre-training on plot table pairs. Specifically, we propose two novel pre-training objectives: Masked Header Prediction (MHP) and Masked Value Prediction (MVP) to facilitate the model with different skills to interpret the table information. We have conducted extensive experiments on chart question answering and chart summarization to verify the effectiveness of the proposed pre-training strategies. In particular, on the ChartQA benchmark, our ChartT5 outperforms the state-of-the-art non-pretraining methods by over 8% performance gains.

Cheng Qian, Chi Han, Yi R. Fung et al.

Large Language Models (LLMs) have made significant progress in utilizing tools, but their ability is limited by API availability and the instability of implicit reasoning, particularly when both planning and execution are involved. To overcome these limitations, we propose CREATOR, a novel framework that enables LLMs to create their own tools using documentation and code realization. CREATOR disentangles abstract tool creation and concrete decision execution, resulting in improved performance. We evaluate CREATOR on MATH and TabMWP benchmarks, respectively consisting of challenging math competition problems and diverse tabular contents. Remarkably, CREATOR outperforms existing chain-of-thought, program-of-thought, and tool-using baselines. Additionally, we introduce the Creation Challenge dataset, featuring 2K diverse questions, to emphasize the necessity and benefits of LLMs' tool creation ability. Further research demonstrates that leveraging LLMs as tool creators facilitates knowledge transfer, and LLMs exhibit varying levels of tool creation abilities, enabling them to adapt to diverse situations. The tool creation ability revolutionizes the LLM's problem-solving paradigm, driving us closer to the next frontier of artificial intelligence. All the codes and data are released.

Revanth Gangi Reddy, Sai Chetan, Zhenhailong Wang et al.

Claim detection and verification are crucial for news understanding and have emerged as promising technologies for mitigating misinformation and disinformation in the news. However, most existing work has focused on claim sentence analysis while overlooking additional crucial attributes (e.g., the claimer and the main object associated with the claim). In this work, we present NewsClaims, a new benchmark for attribute-aware claim detection in the news domain. We extend the claim detection problem to include extraction of additional attributes related to each claim and release 889 claims annotated over 143 news articles. NewsClaims aims to benchmark claim detection systems in emerging scenarios, comprising unseen topics with little or no training data. To this end, we see that zero-shot and prompt-based baselines show promising performance on this benchmark, while still considerably behind human performance.

Spencer Whitehead, Hui Wu, Yi Ren Fung et al.

Existing Visual Question Answering (VQA) models are often fragile and sensitive to input variations. In this paper, we propose a novel approach to address this issue based on modular networks, which creates two questions related by linguistic perturbations and regularizes the visual reasoning process between them to be consistent during training. We show that our framework markedly improves consistency and generalization ability, demonstrating the value of controlled linguistic perturbations as a useful and currently underutilized training and regularization tool for VQA models. We also present VQA Perturbed Pairings (VQA P2), a new, low-cost benchmark and augmentation pipeline to create controllable linguistic variations of VQA questions. Our benchmark uniquely draws from large-scale linguistic resources, avoiding human annotation effort while maintaining data quality compared to generative approaches. We benchmark existing VQA models using VQA P2 and provide robustness analysis on each type of linguistic variation.

Qingyun Wang, Manling Li, Xuan Wang et al.

To combat COVID-19, both clinicians and scientists need to digest vast amounts of relevant biomedical knowledge in scientific literature to understand the disease mechanism and related biological functions. We have developed a novel and comprehensive knowledge discovery framework, COVID-KG to extract fine-grained multimedia knowledge elements (entities and their visual chemical structures, relations, and events) from scientific literature. We then exploit the constructed multimedia knowledge graphs (KGs) for question answering and report generation, using drug repurposing as a case study. Our framework also provides detailed contextual sentences, subfigures, and knowledge subgraphs as evidence.

Richard G. Freedman, Yi Ren Fung, Roman Ganchin et al.

Many intelligent systems currently interact with others using at least one of fixed communication inputs or preset responses, resulting in rigid interaction experiences and extensive efforts developing a variety of scenarios for the system. Fixed inputs limit the natural behavior of the user in order to effectively communicate, and preset responses prevent the system from adapting to the current situation unless it was specifically implemented. Closed-loop interaction instead focuses on dynamic responses that account for what the user is currently doing based on interpretations of their perceived activity. Agents employing closed-loop interaction can also monitor their interactions to ensure that the user responds as expected. We introduce a closed-loop interactive agent framework that integrates planning and recognition to predict what the user is trying to accomplish and autonomously decide on actions to take in response to these predictions. Based on a recent demonstration of such an assistive interactive agent in a turn-based simulated game, we also discuss new research challenges that are not present in the areas of artificial intelligence planning or recognition alone.

Yi Ren Fung, Ziqiang Guan, Ritesh Kumar et al.

In recent years, many papers have reported state-of-the-art performance on Alzheimer's Disease classification with MRI scans from the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset using convolutional neural networks. However, we discover that when we split that data into training and testing sets at the subject level, we are not able to obtain similar performance, bringing the validity of many of the previous studies into question. Furthermore, we point out that previous works use different subsets of the ADNI data, making comparison across similar works tricky. In this study, we present the results of three splitting methods, discuss the motivations behind their validity, and report our results using all of the available subjects.

Surya Teja Devarakonda, Joie Yeahuay Wu, Yi Ren Fung et al.

Computational models that forecast the progression of Alzheimer's disease at the patient level are extremely useful tools for identifying high risk cohorts for early intervention and treatment planning. The state-of-the-art work in this area proposes models that forecast by using latent representations extracted from the longitudinal data across multiple modalities, including volumetric information extracted from medical scans and demographic info. These models incorporate the time horizon, which is the amount of time between the last recorded visit and the future visit, by directly concatenating a representation of it to the data latent representation. In this paper, we present a model which generates a sequence of latent representations of the patient status across the time horizon, providing more informative modeling of the temporal relationships between the patient's history and future visits. Our proposed model outperforms the baseline in terms of forecasting accuracy and F1 score with the added benefit of robustly handling missing visits.

Ziqiang Guan, Ritesh Kumar, Yi Ren Fung et al.

A plethora of deep learning models have been developed for the task of Alzheimer's disease classification from brain MRI scans. Many of these models report high performance, achieving three-class classification accuracy of up to 95%. However, it is common for these studies to draw performance comparisons between models that are trained on different subsets of a dataset or use varying imaging preprocessing techniques, making it difficult to objectively assess model performance. Furthermore, many of these works do not provide details such as hyperparameters, the specific MRI scans used, or their source code, making it difficult to replicate their experiments. To address these concerns, we present a comprehensive study of some of the deep learning methods and architectures on the full set of images available from ADNI. We find that, (1) classification using 3D models gives an improvement of 1% in our setup, at the cost of significantly longer training time and more computation power, (2) with our dataset, pre-training yields minimal ($<0.5\%$) improvement in model performance, (3) most popular convolutional neural network models yield similar performance when compared to each other. Lastly, we briefly compare the effects of two image preprocessing programs: FreeSurfer and Clinica, and find that the spatially normalized and segmented outputs from Clinica increased the accuracy of model prediction from 63% to 89% when compared to FreeSurfer images.