Ignacio E. Grossmann

Christian D. Hubbs, Hector D. Perez, Owais Sarwar et al.

Reinforcement learning (RL) has been widely applied to game-playing and surpassed the best human-level performance in many domains, yet there are few use-cases in industrial or commercial settings. We introduce OR-Gym, an open-source library for developing reinforcement learning algorithms to address operations research problems. In this paper, we apply reinforcement learning to the knapsack, multi-dimensional bin packing, multi-echelon supply chain, and multi-period asset allocation model problems, as well as benchmark the RL solutions against MILP and heuristic models. These problems are used in logistics, finance, engineering, and are common in many business operation settings. We develop environments based on prototypical models in the literature and implement various optimization and heuristic models in order to benchmark the RL results. By re-framing a series of classic optimization problems as RL tasks, we seek to provide a new tool for the operations research community, while also opening those in the RL community to many of the problems and challenges in the OR field.

Daniel Ovalle, Lorenz T. Biegler, Ignacio E. Grossmann et al.

We propose Conformal Mixed-Integer Constraint Learning (C-MICL), a novel framework that provides probabilistic feasibility guarantees for data-driven constraints in optimization problems. While standard Mixed-Integer Constraint Learning methods often violate the true constraints due to model error or data limitations, our C-MICL approach leverages conformal prediction to ensure feasible solutions are ground-truth feasible. This guarantee holds with probability at least $1{-}α$, under a conditional independence assumption. The proposed framework supports both regression and classification tasks without requiring access to the true constraint function, while avoiding the scalability issues associated with ensemble-based heuristics. Experiments on real-world applications demonstrate that C-MICL consistently achieves target feasibility rates, maintains competitive objective performance, and significantly reduces computational cost compared to existing methods. Our work bridges mathematical optimization and machine learning, offering a principled approach to incorporate uncertainty-aware constraints into decision-making with rigorous statistical guarantees.